High-resolution burn imaging in pig skin by photoacoustic microscopy

Hao F. Zhang*, Konstantin Maslov, George Stoica, Lihong V. Wang

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2 Scopus citations

Abstract

Existing noninvasive imaging modalities fail to provide high-resolution depth-resolved imaging of skin burns in large depths. Hence, the measurement of burn depth, especially for partial-thickness burn, remains inaccurate. We used photoacoustic microscopy to measure the depth of acute thermal burns by imaging the microvasculature damage. In this work, partial-thickness burns were induced in vivo on pig skin. Limited by the flexibility of the photoacoustic scanning system, photoacoustic images of the burns were acquired after skin excision. Experimental results show that burn depth increases with longer heating duration. The maximum imaged burn depth measures -1.7 mm with a depth resolution of 15 μm.

Original languageEnglish (US)
Title of host publicationPhotons Plus Ultrasound
Subtitle of host publicationImaging and Sensing 2007: The Eighth Conference on Biomedical Thermoacoustics, Optoacoustics, and Acousto-optics
DOIs
StatePublished - 2007
EventPhotons Plus Ultrasound: Imaging and Sensing 2007: The Eighth Conference on Biomedical Thermoacoustics, Optoacoustics, and Acousto-optics - San Jose, CA, United States
Duration: Jan 21 2007Jan 24 2007

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume6437
ISSN (Print)1605-7422

Other

OtherPhotons Plus Ultrasound: Imaging and Sensing 2007: The Eighth Conference on Biomedical Thermoacoustics, Optoacoustics, and Acousto-optics
CountryUnited States
CitySan Jose, CA
Period1/21/071/24/07

Keywords

  • Burn
  • Microscopy
  • Microvasculature
  • Photoacoustic

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Biomaterials
  • Atomic and Molecular Physics, and Optics
  • Radiology Nuclear Medicine and imaging

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