High-Resolution Manometry: An Atlas of Esophageal Motility Disorders and Findings of GERD Using Esophageal Pressure Topography

High-resolution manometry (HRM) has now become widely available and currently is moving into mainstream clinical practice. This article provides an HRM-related atlas of esophageal motility disorders focused on dysphagia and gastroesophageal reflux disease (GERD). Although there is some overlap between esophageal motor disorders associated with dysphagia and the defects and esophageal motor function that would predispose the patient to more severe GERD, this review is organized to differentiate the distinct pathophysiologic components of the two disease groups. A section on impaired bolus transit is also included to highlight the important aspect of impaired clearance in the pathogenesis of GERD.