High-resolution manometry in clinical practice

Dustin A. Carlson*, John E. Pandolfino

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

22 Scopus citations


High-resolution manometry (HRM) is the primary method used to evaluate esophageal motor function. Displayed and interpreted by esophageal pressure topography (EPT), HRM/EPT provides a detailed assessment of esophageal function that is useful in the evaluation of patients with nonobstructive dysphagia and before foregut surgery. Esophageal motility diagnoses are determined systematically by applying objective metrics of esophageal sphincter and peristaltic function to the Chicago Classification of esophageal motility disorders. This article discusses HRM study, EPT interpretation, and the translation of EPT findings into clinical practice. Examples are provided to illustrate several clinical challenges.

Original languageEnglish (US)
Pages (from-to)374-384
Number of pages11
JournalGastroenterology and Hepatology
Issue number6
StatePublished - Jun 1 2015


  • Achalasia
  • Dysphagia
  • Esophageal pressure topography
  • High-resolution manometry

ASJC Scopus subject areas

  • Hepatology
  • Gastroenterology

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