High-Resolution Neurovascular Imaging at 7T: Arterial Spin Labeling Perfusion, 4-Dimensional MR Angiography, and Black Blood MR Imaging

Xingfeng Shao, Lirong Yan, Samantha J. Ma, Kai Wang, Danny J.J. Wang*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

2 Scopus citations

Abstract

Ultrahigh field offers increased resolution and contrast for neurovascular imaging. Arterial spin labeling methods benefit from an increased intrinsic signal-to-noise ratio of MR imaging signal and a prolonged tracer half-life at ultrahigh field, allowing the visualization of layer-dependent microvascular perfusion. Arterial spin labeling–based time-resolved 4-dimensional MR angiography at 7T provides a detailed depiction of the vascular architecture and dynamic blood flow pattern with high spatial and temporal resolutions. High-resolution black blood MR imaging at 7T allows detailed characterization of small perforating arteries such as lenticulostriate arteries. All techniques benefit from advances in parallel radiofrequency transmission technologies at ultrahigh field.

Original languageEnglish (US)
Pages (from-to)53-65
Number of pages13
JournalMagnetic Resonance Imaging Clinics of North America
Volume29
Issue number1
DOIs
StatePublished - Feb 2021
Externally publishedYes

Keywords

  • 4-Dimensional MR angiography (4D MRA)
  • Arterial spin labeling (ASL)
  • Black blood MR imaging
  • Cortical layer
  • Lenticulostriate arteries (LSA)
  • Perfusion
  • Turbo spin-echo with variable flip angles (TSE VFA)

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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