High spatial resolution whole-neck MR angiography using thin-slab stack-of-stars quiescent interval slice-selective acquisition

Ioannis Koktzoglou; Rong Huang; Archie L. Ong; Pascale J. Aouad; Matthew T. Walker; Robert R. Edelman

doi:10.1002/mrm.28339

High spatial resolution whole-neck MR angiography using thin-slab stack-of-stars quiescent interval slice-selective acquisition

Ioannis Koktzoglou^*, Rong Huang, Archie L. Ong, Pascale J. Aouad, Matthew T. Walker, Robert R. Edelman

^*Corresponding author for this work

Radiology

Research output: Contribution to journal › Article › peer-review

7 Scopus citations

Abstract

Purpose: To report a 3D multi-echo thin-slab stack-of-stars (tsSOS) quiescent-interval slice-selective (QISS) strategy for high-resolution magnetic resonance angiography (MRA) of the entire neck in under seven minutes. Methods: The neck arteries of eight subjects were imaged at 3 Tesla. Multi-echo 3D tsSOS QISS using a FLASH readout was compared with 3D tsSOS FLASH, 2D QISS, 2D TOF, and 3D TOF. A root-mean-square (RMS) combination of echo time images was tested. Evaluation metrics included arterial signal-to-noise ratio (SNR), arterial-to-muscle contrast-to-noise ratio (CNR), and image quality. Results: 3D multi-echo tsSOS QISS using a RMS combination of echo time images increased SNR and CNR by 60% and 63% with respect to the reconstruction obtained with the shortest echo time. 3D tsSOS QISS showed superior CNR with respect to 3D tsSOS FLASH imaging, and more than 3-fold higher SNR and CNR with respect to 2D radial QISS when normalized for voxel size. 3D tsSOS QISS provided good to excellent image quality that exceeded the image quality of 2D QISS, 2D TOF, and 3D TOF (P <.05). Conclusion: Whole-neck high-resolution nonenhanced MRA is feasible using 3D tsSOS QISS, and produced image quality that exceeded those of competing nonenhanced MRA protocols at 3 Tesla.

Original language	English (US)
Pages (from-to)	3316-3324
Number of pages	9
Journal	Magnetic resonance in medicine
Volume	84
Issue number	6
DOIs	https://doi.org/10.1002/mrm.28339
State	Published - Dec 1 2020

Funding

IK: research support (NIH award number R01EB027475; funds paid to institution), intellectual property relating to nonenhanced MR angiography. RRE: intellectual property relating to nonenhanced MR angiography, royalties from Siemens Healthineers. This work was supported in part by the National Institute of Biomedical Imaging and Bioengineering of the National Institutes of Health under Award Number R01EB027475. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health.

Keywords

3D QISS
MRA
carotid
neck
stack of stars
vertebral

ASJC Scopus subject areas

Radiology Nuclear Medicine and imaging

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@article{f61d8cd0e0e947528290cf9355247a18,

title = "High spatial resolution whole-neck MR angiography using thin-slab stack-of-stars quiescent interval slice-selective acquisition",

abstract = "Purpose: To report a 3D multi-echo thin-slab stack-of-stars (tsSOS) quiescent-interval slice-selective (QISS) strategy for high-resolution magnetic resonance angiography (MRA) of the entire neck in under seven minutes. Methods: The neck arteries of eight subjects were imaged at 3 Tesla. Multi-echo 3D tsSOS QISS using a FLASH readout was compared with 3D tsSOS FLASH, 2D QISS, 2D TOF, and 3D TOF. A root-mean-square (RMS) combination of echo time images was tested. Evaluation metrics included arterial signal-to-noise ratio (SNR), arterial-to-muscle contrast-to-noise ratio (CNR), and image quality. Results: 3D multi-echo tsSOS QISS using a RMS combination of echo time images increased SNR and CNR by 60% and 63% with respect to the reconstruction obtained with the shortest echo time. 3D tsSOS QISS showed superior CNR with respect to 3D tsSOS FLASH imaging, and more than 3-fold higher SNR and CNR with respect to 2D radial QISS when normalized for voxel size. 3D tsSOS QISS provided good to excellent image quality that exceeded the image quality of 2D QISS, 2D TOF, and 3D TOF (P <.05). Conclusion: Whole-neck high-resolution nonenhanced MRA is feasible using 3D tsSOS QISS, and produced image quality that exceeded those of competing nonenhanced MRA protocols at 3 Tesla.",

keywords = "3D QISS, MRA, carotid, neck, stack of stars, vertebral",

author = "Ioannis Koktzoglou and Rong Huang and Ong, {Archie L.} and Aouad, {Pascale J.} and Walker, {Matthew T.} and Edelman, {Robert R.}",

note = "Funding Information: IK: research support (NIH award number R01EB027475; funds paid to institution), intellectual property relating to nonenhanced MR angiography. RRE: intellectual property relating to nonenhanced MR angiography, royalties from Siemens Healthineers. Funding Information: This work was supported in part by the National Institute of Biomedical Imaging and Bioengineering of the National Institutes of Health under Award Number R01EB027475. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health. Publisher Copyright: {\textcopyright} 2020 International Society for Magnetic Resonance in Medicine",

year = "2020",

month = dec,

day = "1",

doi = "10.1002/mrm.28339",

language = "English (US)",

volume = "84",

pages = "3316--3324",

journal = "Magnetic resonance in medicine",

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T1 - High spatial resolution whole-neck MR angiography using thin-slab stack-of-stars quiescent interval slice-selective acquisition

AU - Koktzoglou, Ioannis

AU - Huang, Rong

AU - Ong, Archie L.

AU - Aouad, Pascale J.

AU - Walker, Matthew T.

AU - Edelman, Robert R.

N1 - Funding Information: IK: research support (NIH award number R01EB027475; funds paid to institution), intellectual property relating to nonenhanced MR angiography. RRE: intellectual property relating to nonenhanced MR angiography, royalties from Siemens Healthineers. Funding Information: This work was supported in part by the National Institute of Biomedical Imaging and Bioengineering of the National Institutes of Health under Award Number R01EB027475. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health. Publisher Copyright: © 2020 International Society for Magnetic Resonance in Medicine

PY - 2020/12/1

Y1 - 2020/12/1

N2 - Purpose: To report a 3D multi-echo thin-slab stack-of-stars (tsSOS) quiescent-interval slice-selective (QISS) strategy for high-resolution magnetic resonance angiography (MRA) of the entire neck in under seven minutes. Methods: The neck arteries of eight subjects were imaged at 3 Tesla. Multi-echo 3D tsSOS QISS using a FLASH readout was compared with 3D tsSOS FLASH, 2D QISS, 2D TOF, and 3D TOF. A root-mean-square (RMS) combination of echo time images was tested. Evaluation metrics included arterial signal-to-noise ratio (SNR), arterial-to-muscle contrast-to-noise ratio (CNR), and image quality. Results: 3D multi-echo tsSOS QISS using a RMS combination of echo time images increased SNR and CNR by 60% and 63% with respect to the reconstruction obtained with the shortest echo time. 3D tsSOS QISS showed superior CNR with respect to 3D tsSOS FLASH imaging, and more than 3-fold higher SNR and CNR with respect to 2D radial QISS when normalized for voxel size. 3D tsSOS QISS provided good to excellent image quality that exceeded the image quality of 2D QISS, 2D TOF, and 3D TOF (P <.05). Conclusion: Whole-neck high-resolution nonenhanced MRA is feasible using 3D tsSOS QISS, and produced image quality that exceeded those of competing nonenhanced MRA protocols at 3 Tesla.

AB - Purpose: To report a 3D multi-echo thin-slab stack-of-stars (tsSOS) quiescent-interval slice-selective (QISS) strategy for high-resolution magnetic resonance angiography (MRA) of the entire neck in under seven minutes. Methods: The neck arteries of eight subjects were imaged at 3 Tesla. Multi-echo 3D tsSOS QISS using a FLASH readout was compared with 3D tsSOS FLASH, 2D QISS, 2D TOF, and 3D TOF. A root-mean-square (RMS) combination of echo time images was tested. Evaluation metrics included arterial signal-to-noise ratio (SNR), arterial-to-muscle contrast-to-noise ratio (CNR), and image quality. Results: 3D multi-echo tsSOS QISS using a RMS combination of echo time images increased SNR and CNR by 60% and 63% with respect to the reconstruction obtained with the shortest echo time. 3D tsSOS QISS showed superior CNR with respect to 3D tsSOS FLASH imaging, and more than 3-fold higher SNR and CNR with respect to 2D radial QISS when normalized for voxel size. 3D tsSOS QISS provided good to excellent image quality that exceeded the image quality of 2D QISS, 2D TOF, and 3D TOF (P <.05). Conclusion: Whole-neck high-resolution nonenhanced MRA is feasible using 3D tsSOS QISS, and produced image quality that exceeded those of competing nonenhanced MRA protocols at 3 Tesla.

KW - 3D QISS

KW - MRA

KW - carotid

KW - neck

KW - stack of stars

KW - vertebral

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High spatial resolution whole-neck MR angiography using thin-slab stack-of-stars quiescent interval slice-selective acquisition

Abstract

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Keywords

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