High-speed, scanned laser structuring of multi-layered eco/bioresorbable materials for advanced electronic systems

Quansan Yang, Ziying Hu, Min Ho Seo, Yameng Xu, Ying Yan, Yen Hao Hsu, Jaime Berkovich, Kwonjae Lee, Tzu Li Liu, Samantha McDonald, Haolin Nie, Hannah Oh, Mingzheng Wu, Jin Tae Kim, Stephen A. Miller, Ying Jia, Serkan Butun, Wubin Bai, Hexia Guo, Junhwan ChoiAnthony Banks, Wilson Z. Ray, Yevgenia Kozorovitskiy, Matthew L. Becker, Mitchell A. Pet, Matthew R. MacEwan, Jan Kai Chang, Heling Wang*, Yonggang Huang*, John A. Rogers*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

1 Scopus citations


Physically transient forms of electronics enable unique classes of technologies, ranging from biomedical implants that disappear through processes of bioresorption after serving a clinical need to internet-of-things devices that harmlessly dissolve into the environment following a relevant period of use. Here, we develop a sustainable manufacturing pathway, based on ultrafast pulsed laser ablation, that can support high-volume, cost-effective manipulation of a diverse collection of organic and inorganic materials, each designed to degrade by hydrolysis or enzymatic activity, into patterned, multi-layered architectures with high resolution and accurate overlay registration. The technology can operate in patterning, thinning and/or cutting modes with (ultra)thin eco/bioresorbable materials of different types of semiconductors, dielectrics, and conductors on flexible substrates. Component-level demonstrations span passive and active devices, including diodes and field-effect transistors. Patterning these devices into interconnected layouts yields functional systems, as illustrated in examples that range from wireless implants as monitors of neural and cardiac activity, to thermal probes of microvascular flow, and multi-electrode arrays for biopotential sensing. These advances create important processing options for eco/bioresorbable materials and associated electronic systems, with immediate applicability across nearly all types of bioelectronic studies.

Original languageEnglish (US)
Article number6518
JournalNature communications
Issue number1
StatePublished - Dec 2022

ASJC Scopus subject areas

  • General
  • Physics and Astronomy(all)
  • Chemistry(all)
  • Biochemistry, Genetics and Molecular Biology(all)


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