Since most natural tissues, including tendon, skin, bone and blood vessels, contain large amounts of collagen, this protein has long been considered as a logical material for use in the surgical repair of damaged or diseased organs. The ideal collagen biomaterial would be one in which the fibrous structural matrix mimics that of the tissue being repaired or replaced. For example, a tendon prosthesis would have highly oriented linear arrays of collagen fibrils, while an artificial cornea would be composed of layers of orthogonally directed fibril sheets. Described is a new collagen process technology which uses controlled, convection-driven laminar flow to produce oriented fibrillar collagen gels. It was found that, under the correct experimental conditions, collagen could be induced to form oriented gels which can be further processed to yield high-strength ribbons, tapes, filaments and composites.
|Original language||English (US)|
|Number of pages||5|
|Journal||Journal of the American Leather Chemists Association|
|State||Published - Nov 1 1988|
ASJC Scopus subject areas
- Chemical Engineering(all)
- Materials Science(all)