High-volume spinal anesthesia with bupivacaine 0.125% for cesarean section

A. A. Van Zundert, A. M. De Wolf, L. Vaes, M. Soetens

Research output: Contribution to journalArticlepeer-review

30 Scopus citations


This study showed that the suggested test dose for epidural block (10 ml of bupivacaine 0.125% plus epinephrine 1:800,000) is effective and probably safe if injected intrathecally in the obstetric patient; a clearly detectable anesthetic level and motor block are present within a few minutes, without causing an unacceptable high level of anesthesia or hemodynamic decompensation. Hypotension, a common complication of spinal and epidural anesthesia, was never a serious problem in this study despite the fact that intravenous fluid administration was not aggressive. We also showed that the subarachnoid administration of a high-volume, low-concentration bupivacaine solution results in a predictable and solid spinal block which allows cesarean section to be performed without the least discomfort to the patient and without any obvious harm to the fetus.

Original languageEnglish (US)
Pages (from-to)998-1003
Number of pages6
Issue number6
StatePublished - 1988

ASJC Scopus subject areas

  • Anesthesiology and Pain Medicine


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