Hip Arthroscopy With Bone Marrow Aspirate Injection for Patients With Symptomatic Labral Tears and Early Degenerative Changes Shows Similar Improvement Compared With Patients Undergoing Hip Arthroscopy With Symptomatic Labral Tears Without Arthritis

Molly A. Day*, Kyle J. Hancock, Ryan S. Selley, Reena Olsen, Anil S. Ranawat, Benedict U. Nwachukwu, Bryan T. Kelly, Danyal H. Nawabi

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

12 Scopus citations

Abstract

Purpose: To define the clinical effect of intra-articular injection of iliac crest–derived bone marrow aspirate concentrate (BMAC) at the time of hip arthroscopy in patients with symptomatic labral tears and early radiographic degenerative changes. Methods: A retrospective review of a prospectively collected hip registry database was performed. Patients with symptomatic labral tears and Tönnis grade 1 or 2 degenerative changes who underwent labrum-preserving hip arthroscopy with BMAC injection were included and were matched with patients who underwent hip arthroscopy without BMAC injection. Patient-reported outcomes (PROs) collected preoperatively and up to 2 years postoperatively included the modified Harris Hip Score, Hip Outcome Score–Activities of Daily Living, Hip Outcome Score–Sport, and International Hip Outcome Tool 33 score. Clinical relevance was measured with the minimal clinically important difference, patient acceptable symptom state, and substantial clinical benefit for each outcome score. Results: A total of 35 patients underwent labrum-preserving hip arthroscopy with BMAC injection and were matched with 35 control patients. There were no differences in demographic characteristics between the groups (P > .05). The BMAC group consisted of 22 patients (62.9%) with Tönnis grade 1 changes and 13 (37.1%) with Tönnis grade 2 changes, whereas all 35 control patients had Tönnis grade 0 hips. All PROs were significantly improved in both groups at 2 years, with no difference in improvement. The rate of failure requiring conversion to total hip arthroplasty was 14.3% (mean, 1.6 years postoperatively) in the BMAC group and 5.7% (mean, 7 years postoperatively) in the control group (P = .09). The difference in the frequency of patients achieving the minimal clinically important difference, patient acceptable symptom state, and substantial clinical benefit was not statistically significant between cohorts. Conclusions: In a challenging group of patients with symptomatic labral tears and early radiographic degenerative changes, hip arthroscopy with BMAC injection results in statistically and clinically significant improvement in PROs comparable to a group of patients with nonarthritic hips undergoing hip arthroscopy at short-term follow-up. Level of Evidence: Level III, retrospective comparative therapeutic trial.

Original languageEnglish (US)
Pages (from-to)1429-1437
Number of pages9
JournalArthroscopy - Journal of Arthroscopic and Related Surgery
Volume39
Issue number6
DOIs
StatePublished - Jun 2023

Funding

The authors report the following potential conflicts of interest or sources of funding: A.S.R. is a paid consultant for Arthrex, Ceramtec, Medtronic, Moximed, Pfizer, and Smith & Nephew; owns stock or stock options in ConforMIS and Enhatch; receives research support from DePuy Mitek-Synthes and Stryker; and receives intellectual property royalties from DePuy (A Johnson & Johnson Company) and Stryker Mako, outside the submitted work. Full ICMJE author disclosure forms are available for this article online, as supplementary material.

ASJC Scopus subject areas

  • Orthopedics and Sports Medicine

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