Histopathologic changes after pericardial patch tracheoplasty

Alan T L Cheng; Carl L. Bacher; Lauren D. Holinger; Michael E. Dunham; Constanüne Mavroudis; Franh Gonzalez-Cnissi

doi:10.1001/archotol.1997.01900100043006

Histopathologic changes after pericardial patch tracheoplasty

Alan T L Cheng, Carl L. Bacher, Lauren D. Holinger, Michael E. Dunham, Constanüne Mavroudis, Franh Gonzalez-Cnissi

Surgery, Cardiac Surgery Division

Research output: Contribution to journal › Article › peer-review

40 Scopus citations

Abstract

Pericardial patch tracheoplasty has been used for surgical correction of long-segment congenital tracheal stenosis caused by complete tracheal rings in infants. The case histories of 2 infants with descriptions of the histopathologic changes in their respective tracheas are presented. Complete reepithelialization of the graft site with ciliated pseudostratified columnar epithelium was found, suggesting the likelihood of normal mucociliary flow in the trachea. The pericardial patches were replaced by mature scar tissue in the graft site, establishing a functional tracheal lumen. Wound healing in the trachea is reviewed. Obstruction by exuberant granulation tissue is an ongoing concern. Pericardium continues to be an important option as graft material for tracheal reconstruction in infants with long-segment congenital tracheal stenosis.

Original language	English (US)
Pages (from-to)	1069-1072
Number of pages	4
Journal	Archives of Otolaryngology - Head and Neck Surgery
Volume	123
Issue number	10
DOIs	https://doi.org/10.1001/archotol.1997.01900100043006
State	Published - Oct 1997

ASJC Scopus subject areas

Surgery
Otorhinolaryngology

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10.1001/archotol.1997.01900100043006

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title = "Histopathologic changes after pericardial patch tracheoplasty",

abstract = "Pericardial patch tracheoplasty has been used for surgical correction of long-segment congenital tracheal stenosis caused by complete tracheal rings in infants. The case histories of 2 infants with descriptions of the histopathologic changes in their respective tracheas are presented. Complete reepithelialization of the graft site with ciliated pseudostratified columnar epithelium was found, suggesting the likelihood of normal mucociliary flow in the trachea. The pericardial patches were replaced by mature scar tissue in the graft site, establishing a functional tracheal lumen. Wound healing in the trachea is reviewed. Obstruction by exuberant granulation tissue is an ongoing concern. Pericardium continues to be an important option as graft material for tracheal reconstruction in infants with long-segment congenital tracheal stenosis.",

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AU - Cheng, Alan T L

AU - Bacher, Carl L.

AU - Holinger, Lauren D.

AU - Dunham, Michael E.

AU - Mavroudis, Constanüne

AU - Gonzalez-Cnissi, Franh

PY - 1997/10

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N2 - Pericardial patch tracheoplasty has been used for surgical correction of long-segment congenital tracheal stenosis caused by complete tracheal rings in infants. The case histories of 2 infants with descriptions of the histopathologic changes in their respective tracheas are presented. Complete reepithelialization of the graft site with ciliated pseudostratified columnar epithelium was found, suggesting the likelihood of normal mucociliary flow in the trachea. The pericardial patches were replaced by mature scar tissue in the graft site, establishing a functional tracheal lumen. Wound healing in the trachea is reviewed. Obstruction by exuberant granulation tissue is an ongoing concern. Pericardium continues to be an important option as graft material for tracheal reconstruction in infants with long-segment congenital tracheal stenosis.

AB - Pericardial patch tracheoplasty has been used for surgical correction of long-segment congenital tracheal stenosis caused by complete tracheal rings in infants. The case histories of 2 infants with descriptions of the histopathologic changes in their respective tracheas are presented. Complete reepithelialization of the graft site with ciliated pseudostratified columnar epithelium was found, suggesting the likelihood of normal mucociliary flow in the trachea. The pericardial patches were replaced by mature scar tissue in the graft site, establishing a functional tracheal lumen. Wound healing in the trachea is reviewed. Obstruction by exuberant granulation tissue is an ongoing concern. Pericardium continues to be an important option as graft material for tracheal reconstruction in infants with long-segment congenital tracheal stenosis.

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Histopathologic changes after pericardial patch tracheoplasty

Abstract

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