HIV-1 drug resistance assays in clinical management.

J. Martinez-Picado*, R. D'Aquila

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

3 Scopus citations


Current antiretroviral therapy is based on combinations of three or more drugs which reduce viral loads to undetectable levels, leading to clinical improvement in most patients. These therapies require significant monitoring, and HIV RNA levels and CD4 cell counts should be the main laboratory criteria for judging the effectiveness of the treatment. There are two types of assays that can determine drug resistance: genotypic assays and phenotypic assays. The mechanics, benefits, and shortcomings of both tests are described.

Original languageEnglish (US)
JournalAIDS clinical care
Issue number11
StatePublished - Jan 1 1998

ASJC Scopus subject areas

  • General Medicine


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