HIV-associated distal symmetrical poly neuropathy: Clinical features and nursing management

Barbara Swanson, Janice M. Zeller, Judith A. Paice

Research output: Contribution to journalReview articlepeer-review

16 Scopus citations


DSPN is a common manifestation of HIV infection and/or its treatment that can have adverse effects on quality of life and functional status. The pathogenesis remains unclear but likely involves the elaboration of neurotoxic inflammatory cytokines and their metabolites. DSPN is often refractory to available pharmacological treatments, although new treatments involving NGF hold promise for effecting sustained symptom relief and reversing axonal degeneration. Further research is needed to determine the efficacy of nonpharmacological treatments, such as cognitivebehavioral therapies, to alleviate DSPN-associated pain.

Original languageEnglish (US)
Pages (from-to)77-80
Number of pages4
JournalJournal of the Association of Nurses in AIDS Care
Issue number2
StatePublished - Jan 1 1998

ASJC Scopus subject areas

  • Advanced and Specialized Nursing


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