TY - JOUR
T1 - HIV-associated distal symmetrical poly neuropathy
T2 - Clinical features and nursing management
AU - Swanson, Barbara
AU - Zeller, Janice M.
AU - Paice, Judith A.
PY - 1998/1/1
Y1 - 1998/1/1
N2 - DSPN is a common manifestation of HIV infection and/or its treatment that can have adverse effects on quality of life and functional status. The pathogenesis remains unclear but likely involves the elaboration of neurotoxic inflammatory cytokines and their metabolites. DSPN is often refractory to available pharmacological treatments, although new treatments involving NGF hold promise for effecting sustained symptom relief and reversing axonal degeneration. Further research is needed to determine the efficacy of nonpharmacological treatments, such as cognitivebehavioral therapies, to alleviate DSPN-associated pain.
AB - DSPN is a common manifestation of HIV infection and/or its treatment that can have adverse effects on quality of life and functional status. The pathogenesis remains unclear but likely involves the elaboration of neurotoxic inflammatory cytokines and their metabolites. DSPN is often refractory to available pharmacological treatments, although new treatments involving NGF hold promise for effecting sustained symptom relief and reversing axonal degeneration. Further research is needed to determine the efficacy of nonpharmacological treatments, such as cognitivebehavioral therapies, to alleviate DSPN-associated pain.
UR - http://www.scopus.com/inward/record.url?scp=0032010750&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0032010750&partnerID=8YFLogxK
U2 - 10.1016/S1055-3290(98)80063-0
DO - 10.1016/S1055-3290(98)80063-0
M3 - Review article
C2 - 9513138
AN - SCOPUS:0032010750
SN - 1055-3290
VL - 9
SP - 77
EP - 80
JO - Journal of the Association of Nurses in AIDS Care
JF - Journal of the Association of Nurses in AIDS Care
IS - 2
ER -
