HIV-associated neurologic disease incidence changes: Multicenter AIDS Cohort Study, 1990-1998

Ned Sacktor*, R. H. Lyles, R. Skolasky, C. Kleeberger, O. A. Selnes, E. N. Miller, J. T. Becker, B. Cohen, J. C. McArthur

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

531 Scopus citations

Abstract

This study examined the temporal trends in the incidence rates of HIV dementia, cryptococcal meningitis, toxoplasmosis, progressive multifocal leukoencephalopathy, and CNS lymphoma from January 1990 to December 1998 in the Multicenter AIDS Cohort Study. The incidence rates for HIV dementia, cryptococcal meningitis, and lymphoma decreased following the introduction of highly active antiretroviral therapy (HAART). The proportion of new cases of HIV dementia with a CD4 count in a higher range (i.e., 201 to 350) since 1996 may be increasing.

Original languageEnglish (US)
Pages (from-to)257-260
Number of pages4
JournalNeurology
Volume56
Issue number2
DOIs
StatePublished - Jan 23 2001

ASJC Scopus subject areas

  • Clinical Neurology

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