HIV infection of the genital mucosa in women

Florian Hladik*, Thomas J. Hope

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

147 Scopus citations

Abstract

The vast majority of new HIV infections are acquired via the genital and rectal mucosa. Here, we provide an overview of our current knowledge of how HIV establishes local infection, with an emphasis on viral invasion through the female genital tract. Studies using human explant tissues and in vivo animal studies have improved our understanding of the cellular and molecular pathways of infection; this information could be harnessed to design effective HIV vaccines and microbicides.

Original languageEnglish (US)
Pages (from-to)20-28
Number of pages9
JournalCurrent HIV/AIDS Reports
Volume6
Issue number1
DOIs
StatePublished - Feb 2009

ASJC Scopus subject areas

  • Virology
  • Infectious Diseases

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