HIV Treatment Cascade and PrEP Care Continuum Among Serodiscordant Male Couples in the United States

Harry Jin; Katie B. Biello; Robert Garofalo; Mark Lurie; Patrick S. Sullivan; Rob Stephenson; Matthew J. Mimiaga

doi:10.1007/s10461-021-03315-8

HIV Treatment Cascade and PrEP Care Continuum Among Serodiscordant Male Couples in the United States

Harry Jin^*, Katie B. Biello, Robert Garofalo, Mark Lurie, Patrick S. Sullivan, Rob Stephenson, Matthew J. Mimiaga

^*Corresponding author for this work

Pediatrics

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Abstract

A large proportion of HIV infections among men who have sex with men occur within primary partnerships, however, there is a lack of research focused on serodiscordant male couples. We used baseline data collected as part of Project Stronger Together—a randomized controlled trial to improve treatment outcomes among 155 serodiscordant male couples. We described engagement in HIV care/prevention using the HIV treatment cascade and PrEP care continuum. Among partners living with HIV, 86.5% were linked to care, 77.4% retained in care, 81.3% prescribed ART, 60.7% adherent, and 67.7%virally suppressed. Among HIV-negative partners, 62.6% were willing to take PrEP, 48.4% had ever taken PrEP, and 26.5% were adherent to PrEP. Black partners living with HIV had lower odds of being virally suppressed compared to White partners. Our findings provide evidence to suggest designing programs to address the racial disparities in viral suppression, addressing barriers to HIV prevention/treatment, and improving PrEP education.

Original language	English (US)
Pages (from-to)	3563-3573
Number of pages	11
Journal	AIDS and behavior
Volume	25
Issue number	11
DOIs	https://doi.org/10.1007/s10461-021-03315-8
State	Published - Nov 2021

Funding

No authors listed on this manuscript has conflicts of interest to report. H. Jin was supported by the U.S. NIH, NIAID, T32 Training Program in HIV Epidemiology and Prevention Science at the Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health (5T32AI102623-08). Research reported in this publication was supported by the Eunice Kennedy Shriver National Institute of Child Health & Human Development of the National Institutes of Health under Award Number R01HD075655 (MPIs: Drs. Garofalo, Mimiaga, and Stephenson). The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health.

Keywords

Antiretroviral therapy
Engagement in care
Men who have sex with men
Pre-exposure prophylaxis
Serodiscordant

ASJC Scopus subject areas

Public Health, Environmental and Occupational Health
Infectious Diseases
Social Psychology

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1007/s10461-021-03315-8

Cite this

@article{7ce8c4a9727646dcaf04f14a810771b8,

title = "HIV Treatment Cascade and PrEP Care Continuum Among Serodiscordant Male Couples in the United States",

abstract = "A large proportion of HIV infections among men who have sex with men occur within primary partnerships, however, there is a lack of research focused on serodiscordant male couples. We used baseline data collected as part of Project Stronger Together—a randomized controlled trial to improve treatment outcomes among 155 serodiscordant male couples. We described engagement in HIV care/prevention using the HIV treatment cascade and PrEP care continuum. Among partners living with HIV, 86.5% were linked to care, 77.4% retained in care, 81.3% prescribed ART, 60.7% adherent, and 67.7%virally suppressed. Among HIV-negative partners, 62.6% were willing to take PrEP, 48.4% had ever taken PrEP, and 26.5% were adherent to PrEP. Black partners living with HIV had lower odds of being virally suppressed compared to White partners. Our findings provide evidence to suggest designing programs to address the racial disparities in viral suppression, addressing barriers to HIV prevention/treatment, and improving PrEP education.",

keywords = "Antiretroviral therapy, Engagement in care, Men who have sex with men, Pre-exposure prophylaxis, Serodiscordant",

author = "Harry Jin and Biello, {Katie B.} and Robert Garofalo and Mark Lurie and Sullivan, {Patrick S.} and Rob Stephenson and Mimiaga, {Matthew J.}",

note = "Funding Information: No authors listed on this manuscript has conflicts of interest to report. H. Jin was supported by the U.S. NIH, NIAID, T32 Training Program in HIV Epidemiology and Prevention Science at the Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health (5T32AI102623-08). Research reported in this publication was supported by the Eunice Kennedy Shriver National Institute of Child Health & Human Development of the National Institutes of Health under Award Number R01HD075655 (MPIs: Drs. Garofalo, Mimiaga, and Stephenson). The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health. Publisher Copyright: {\textcopyright} 2021, The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.",

year = "2021",

month = nov,

doi = "10.1007/s10461-021-03315-8",

language = "English (US)",

volume = "25",

pages = "3563--3573",

journal = "AIDS and behavior",

issn = "1090-7165",

publisher = "Springer New York",

number = "11",

}

TY - JOUR

T1 - HIV Treatment Cascade and PrEP Care Continuum Among Serodiscordant Male Couples in the United States

AU - Jin, Harry

AU - Biello, Katie B.

AU - Garofalo, Robert

AU - Lurie, Mark

AU - Sullivan, Patrick S.

AU - Stephenson, Rob

AU - Mimiaga, Matthew J.

N1 - Funding Information: No authors listed on this manuscript has conflicts of interest to report. H. Jin was supported by the U.S. NIH, NIAID, T32 Training Program in HIV Epidemiology and Prevention Science at the Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health (5T32AI102623-08). Research reported in this publication was supported by the Eunice Kennedy Shriver National Institute of Child Health & Human Development of the National Institutes of Health under Award Number R01HD075655 (MPIs: Drs. Garofalo, Mimiaga, and Stephenson). The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health. Publisher Copyright: © 2021, The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.

PY - 2021/11

Y1 - 2021/11

N2 - A large proportion of HIV infections among men who have sex with men occur within primary partnerships, however, there is a lack of research focused on serodiscordant male couples. We used baseline data collected as part of Project Stronger Together—a randomized controlled trial to improve treatment outcomes among 155 serodiscordant male couples. We described engagement in HIV care/prevention using the HIV treatment cascade and PrEP care continuum. Among partners living with HIV, 86.5% were linked to care, 77.4% retained in care, 81.3% prescribed ART, 60.7% adherent, and 67.7%virally suppressed. Among HIV-negative partners, 62.6% were willing to take PrEP, 48.4% had ever taken PrEP, and 26.5% were adherent to PrEP. Black partners living with HIV had lower odds of being virally suppressed compared to White partners. Our findings provide evidence to suggest designing programs to address the racial disparities in viral suppression, addressing barriers to HIV prevention/treatment, and improving PrEP education.

AB - A large proportion of HIV infections among men who have sex with men occur within primary partnerships, however, there is a lack of research focused on serodiscordant male couples. We used baseline data collected as part of Project Stronger Together—a randomized controlled trial to improve treatment outcomes among 155 serodiscordant male couples. We described engagement in HIV care/prevention using the HIV treatment cascade and PrEP care continuum. Among partners living with HIV, 86.5% were linked to care, 77.4% retained in care, 81.3% prescribed ART, 60.7% adherent, and 67.7%virally suppressed. Among HIV-negative partners, 62.6% were willing to take PrEP, 48.4% had ever taken PrEP, and 26.5% were adherent to PrEP. Black partners living with HIV had lower odds of being virally suppressed compared to White partners. Our findings provide evidence to suggest designing programs to address the racial disparities in viral suppression, addressing barriers to HIV prevention/treatment, and improving PrEP education.

KW - Antiretroviral therapy

KW - Engagement in care

KW - Men who have sex with men

KW - Pre-exposure prophylaxis

KW - Serodiscordant

UR - http://www.scopus.com/inward/record.url?scp=85106697717&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85106697717&partnerID=8YFLogxK

U2 - 10.1007/s10461-021-03315-8

DO - 10.1007/s10461-021-03315-8

M3 - Article

C2 - 34046761

AN - SCOPUS:85106697717

SN - 1090-7165

VL - 25

SP - 3563

EP - 3573

JO - AIDS and behavior

JF - AIDS and behavior

IS - 11

ER -

HIV Treatment Cascade and PrEP Care Continuum Among Serodiscordant Male Couples in the United States

Abstract

Funding

Keywords

ASJC Scopus subject areas

UN SDGs

Access to Document

Other files and links

Fingerprint

Cite this