How blood shear stress regulates vascular smooth muscle cell migration

Shu Qian Liu*, Lin Zhong, Jeremy Goldman

*Corresponding author for this work

Research output: Contribution to journalConference articlepeer-review

Abstract

We have developed an experimental model to induce SMC migration in vivo and to assess the shear influence on this activity. In this model, a 350 micron polymeric cylinder was implanted into the rat abdominal vena cava through the vessel center with the cylinder axis perpendicular to blood flow. Results suggest that blood shear stress regulates SMC migration, and endothelial cells possibly mediate this process.

Original languageEnglish (US)
JournalAnnals of Biomedical Engineering
Volume28
Issue numberSUPPL. 1
StatePublished - Dec 1 2000
Event2000 Annual Fall Meeting of the Biomedical Engineering Society - Washington, WA, USA
Duration: Oct 12 2000Oct 14 2000

ASJC Scopus subject areas

  • Biomedical Engineering

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