How to target vascular leakage in retinopathy: could a lipid tighten the pipes?

M. Luisa Iruela-Arispe*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

Retinopathy is one of the more severe complications associated with diabetes. Targeting vascular pathology has shown benefits, but current therapies are costly and have limitations. In this issue of EMBO Molecular Medicine, Niaudet et al report that the activation of the S1PR1 receptor in endothelial cells is able to block abnormal permeability, neovascular tuft development, and resolve pathological vascular lesions associated with hypoxia-driven retinopathy.

Original languageEnglish (US)
Article numbere17520
JournalEMBO Molecular Medicine
Volume15
Issue number5
DOIs
StatePublished - May 8 2023

ASJC Scopus subject areas

  • Molecular Medicine

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