Human chorionic gonadotropin and malignant mesothelioma

Stuart Rich, Cary A. Presant*, John Meyer, Sue C. Stevens, David Carr

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

9 Scopus citations

Abstract

A 56‐year‐old male presented with ascites and gynecomastia. Laparoscopy demonstrated peritoneal tumors which were biopsied. Conventional histology and electron microscopy revealed the tumor to be a malignant mesothelioma. The ascitic fluid and tumor cell lysate, but not serum, contained hCG by specific assay, and the immunoreactive hCG had characteristics similar to purified hCG in filtration on Sephadex G‐100. Malignant mesothelioma is a tumor which may be associated with elevated hCG concentrations. Demonstration of hCG in ascitic fluid should suggest the presence of neoplasm.

Original languageEnglish (US)
Pages (from-to)1457-1462
Number of pages6
JournalCancer
Volume43
Issue number4
DOIs
StatePublished - Jan 1 1979

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

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