Human chorionic gonadotropin and malignant mesothelioma

Stuart Rich; Cary A. Presant; John Meyer; Sue C. Stevens; David Carr

doi:10.1002/1097-0142(197904)43:4<1457::AID-CNCR2820430436>3.0.CO;2-8

Human chorionic gonadotropin and malignant mesothelioma

Stuart Rich, Cary A. Presant^*, John Meyer, Sue C. Stevens, David Carr

^*Corresponding author for this work

Medicine, Cardiology Division

Research output: Contribution to journal › Article › peer-review

9 Scopus citations

Abstract

A 56‐year‐old male presented with ascites and gynecomastia. Laparoscopy demonstrated peritoneal tumors which were biopsied. Conventional histology and electron microscopy revealed the tumor to be a malignant mesothelioma. The ascitic fluid and tumor cell lysate, but not serum, contained hCG by specific assay, and the immunoreactive hCG had characteristics similar to purified hCG in filtration on Sephadex G‐100. Malignant mesothelioma is a tumor which may be associated with elevated hCG concentrations. Demonstration of hCG in ascitic fluid should suggest the presence of neoplasm.

Original language	English (US)
Pages (from-to)	1457-1462
Number of pages	6
Journal	cancer
Volume	43
Issue number	4
DOIs	https://doi.org/10.1002/1097-0142(197904)43:4<1457::AID-CNCR2820430436>3.0.CO;2-8
State	Published - Apr 1979

ASJC Scopus subject areas

Oncology
Cancer Research

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10.1002/1097-0142(197904)43:4<1457::AID-CNCR2820430436>3.0.CO;2-8

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title = "Human chorionic gonadotropin and malignant mesothelioma",

abstract = "A 56‐year‐old male presented with ascites and gynecomastia. Laparoscopy demonstrated peritoneal tumors which were biopsied. Conventional histology and electron microscopy revealed the tumor to be a malignant mesothelioma. The ascitic fluid and tumor cell lysate, but not serum, contained hCG by specific assay, and the immunoreactive hCG had characteristics similar to purified hCG in filtration on Sephadex G‐100. Malignant mesothelioma is a tumor which may be associated with elevated hCG concentrations. Demonstration of hCG in ascitic fluid should suggest the presence of neoplasm.",

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AU - Rich, Stuart

AU - Presant, Cary A.

AU - Meyer, John

AU - Stevens, Sue C.

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N2 - A 56‐year‐old male presented with ascites and gynecomastia. Laparoscopy demonstrated peritoneal tumors which were biopsied. Conventional histology and electron microscopy revealed the tumor to be a malignant mesothelioma. The ascitic fluid and tumor cell lysate, but not serum, contained hCG by specific assay, and the immunoreactive hCG had characteristics similar to purified hCG in filtration on Sephadex G‐100. Malignant mesothelioma is a tumor which may be associated with elevated hCG concentrations. Demonstration of hCG in ascitic fluid should suggest the presence of neoplasm.

AB - A 56‐year‐old male presented with ascites and gynecomastia. Laparoscopy demonstrated peritoneal tumors which were biopsied. Conventional histology and electron microscopy revealed the tumor to be a malignant mesothelioma. The ascitic fluid and tumor cell lysate, but not serum, contained hCG by specific assay, and the immunoreactive hCG had characteristics similar to purified hCG in filtration on Sephadex G‐100. Malignant mesothelioma is a tumor which may be associated with elevated hCG concentrations. Demonstration of hCG in ascitic fluid should suggest the presence of neoplasm.

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Human chorionic gonadotropin and malignant mesothelioma

Abstract

ASJC Scopus subject areas

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