TY - JOUR
T1 - Human Protein Reference Database - 2009 update
AU - Keshava Prasad, T. S.
AU - Goel, Renu
AU - Kandasamy, Kumaran
AU - Keerthikumar, Shivakumar
AU - Kumar, Sameer
AU - Mathivanan, Suresh
AU - Telikicherla, Deepthi
AU - Raju, Rajesh
AU - Shafreen, Beema
AU - Venugopal, Abhilash
AU - Balakrishnan, Lavanya
AU - Marimuthu, Arivusudar
AU - Banerjee, Sutopa
AU - Somanathan, Devi S.
AU - Sebastian, Aimy
AU - Rani, Sandhya
AU - Ray, Somak
AU - Harrys Kishore, C. J.
AU - Kanth, Sashi
AU - Ahmed, Mukhtar
AU - Kashyap, Manoj K.
AU - Mohmood, Riaz
AU - Ramachandra, Y. I.
AU - Krishna, V.
AU - Rahiman, B. Abdul
AU - Mohan, Sujatha
AU - Ranganathan, Prathibha
AU - Ramabadran, Subhashri
AU - Chaerkady, Raghothama
AU - Pandey, Akhilesh
PY - 2009
Y1 - 2009
N2 - Human Protein Reference Database HPRD-http://www.hprd.org/), initially described in 2003, is a database of curated proteomic information pertaining to human proteins. We have recently added a number of new features in HPRD. These include PhosphoMotif Finder, which allows users to find the presence of over 320 experimentally verified phosphorylation motifs in proteins of interest. Another new feature is a protein distributed annotation system-Human Proteinpedia http://www.humanproteinpedia.org/) - through which laboratories can submit their data, which is mapped onto protein entries in HPRD. Over 75 laboratories involved in proteomics research have already participated in this effort by submitting data for over 15 000 human proteins. The submitted data includes mass spectrometry and protein microarray-derived data, among other data types. Finally, HPRD is also linked to a compendium of human signaling pathways developed by our group, NetPath (http://www.netpath.org/), which currently contains annotations for several cancer and immune signaling pathways. Since the last update, more than 5500 new protein sequences have been added, making HPRD a comprehensive resource for studying the human proteome.
AB - Human Protein Reference Database HPRD-http://www.hprd.org/), initially described in 2003, is a database of curated proteomic information pertaining to human proteins. We have recently added a number of new features in HPRD. These include PhosphoMotif Finder, which allows users to find the presence of over 320 experimentally verified phosphorylation motifs in proteins of interest. Another new feature is a protein distributed annotation system-Human Proteinpedia http://www.humanproteinpedia.org/) - through which laboratories can submit their data, which is mapped onto protein entries in HPRD. Over 75 laboratories involved in proteomics research have already participated in this effort by submitting data for over 15 000 human proteins. The submitted data includes mass spectrometry and protein microarray-derived data, among other data types. Finally, HPRD is also linked to a compendium of human signaling pathways developed by our group, NetPath (http://www.netpath.org/), which currently contains annotations for several cancer and immune signaling pathways. Since the last update, more than 5500 new protein sequences have been added, making HPRD a comprehensive resource for studying the human proteome.
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U2 - 10.1093/nar/gkn892
DO - 10.1093/nar/gkn892
M3 - Article
C2 - 18988627
AN - SCOPUS:58149193222
SN - 0305-1048
VL - 37
SP - D767-D772
JO - Nucleic acids research
JF - Nucleic acids research
IS - SUPPL. 1
ER -