Human stem cells for modeling heart disease and for drug discovery

Elena Matsa, Paul W. Burridge, Joseph C. Wu*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

118 Scopus citations

Abstract

A major research focus in the field of cardiovascular medicine is the prospect of using stem cells and progenitor cells for cardiac regeneration. With the advent of induced pluripotent stem cell (iPSC) technology, major efforts are also underway to use iPSCs to model heart disease, to screen for new drugs, and to test candidate drugs for cardiotoxicity. Here, we discuss recent advances in the exciting fields of stem cells and cardiovascular disease.

Original languageEnglish (US)
Article number239ps6
JournalScience translational medicine
Volume6
Issue number239
DOIs
StatePublished - Jun 4 2014

ASJC Scopus subject areas

  • Medicine(all)

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