Human T-cell lymphotrophic virus type-I (HTLV-I) retrovirus and human disease

David J. Bentrem, Elizabeth E. McGovern, Marie Louise Hammarskjöld, Richard F. Edlich*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

5 Scopus citations


Human T-cell lymphotrophic virus type-I (HTLV-I) was the first pathogenic retrovirus identified in humans. HTLV-I is now linked to a number of clinical diseases, most notably adult T-cell leukemia/lymphoma and the syndrome known as HTLV-associated myelopathy or tropical spastic paraparesis (HAM/TSP). For the emergency physician practicing among patients from high-risk groups, HTLV-I infection and its associated diseases are presenting an increasing challenge. This report describes its transmission, seroprevalence, associated diseases, and methods to control the spread of this retrovirus.

Original languageEnglish (US)
Pages (from-to)825-832
Number of pages8
JournalJournal of Emergency Medicine
Issue number6
StatePublished - 1994


  • adult T-cell leukemia/lymphoma
  • human T-cell lymphotrophic virus type I-II
  • tropical spastic paraparesis

ASJC Scopus subject areas

  • Emergency Medicine


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