Human T-cell lymphotropic virus type I-associated adult T-cell leukemia/lymphoma in an atypical host

Robin G Leikin, C. V. Herst, M. S. Kies, D. Variakojis, R. J. Marder, S. T. Rosen

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Abstract

Human T-cell lymphotropic virus type I (HTLV-I) is a unique retrovirus associated with specific malignancies of T cells in humans. The virus is endemic to Japan, the Caribbean, Africa, and the southeastern United States. We report here the first case of HTLV-I-associated lymphoma in an atypical host. The incidence of antibodies in this individual with a T-cell malignancy strongly suggests HTLV-I virus as the causative agent. Direct identification of viral DNA using an HTLV-I-specific probe provides definitive evidence of infection.

Original languageEnglish (US)
Pages (from-to)1054-1056
Number of pages3
JournalArchives of Pathology and Laboratory Medicine
Volume111
Issue number11
Publication statusPublished - Dec 1 1987

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ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Medical Laboratory Technology

Cite this

Leikin, R. G., Herst, C. V., Kies, M. S., Variakojis, D., Marder, R. J., & Rosen, S. T. (1987). Human T-cell lymphotropic virus type I-associated adult T-cell leukemia/lymphoma in an atypical host. Archives of Pathology and Laboratory Medicine, 111(11), 1054-1056.