IT is well known that the ability of the kidneys to concentrate urine is impaired by obstruction of the urinary tract.1 2 3 Nephrogenic diabetes insipidus4 5 6 7 has been shown to occur both with partial Urinary Tract obstruction and in the course of postobstructive diuresis after relief of complete urinary-tract obstruction. That severe hypernatremia and hyperosmolar dehydration may occur in certain patients with partial urinary-tract obstruction, however, is not generally appreciated. Thus, a recent review of hypernatremia8 and two standard textbook chapters9,10 on obstructive uropathy do not describe this phenomenon. The course of two illustrative patients seen over the past five years with.
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