@article{b324f39c8c5841a383f5e0f032f62b0b,
title = "Hypertension in the elderly",
abstract = "The available data indicate that classical hypertension, defined here as a diastolic blood pressure ≥95 mm Hg, is a widely prevalent and as important a risk factor for the cardiovascular diseases in those aged 65 and over as it is in those under 65. The limited available data also indicate that pure systolic hypertension, defined here as a systolic blood pressure exceeding 160 mm Hg with a diastolic pressure under 95 mm Hg, also very common at age 65 and over, is also related to excess cardiovascular morbidity and mortality in the elderly. However, it is not clear whether this latter relationship is indicative of cause and effect, or merely reflects the fact that in the elderly pure systolic hypertension is a sign of extensive sclerosis of large arteries. The results of Veterans Administration studies on antihypertensive therapy indicate that the elderly patient with classical hypertension is amenable to effective treatment, and that the benefits of such treatment significantly outweigh the risks. Great care is needed in the use of drugs for the management of hypertension in elderly patients, especially to minimize risk of hypotensive episodes and their possible harmful consequences; buth with judicious and careful therapy, hypertension of this type can be controlled with reduction in excess risk of morbidity and mortality, at least for those with average diastolic pressures ≥105 mm Hg. The lack of data on the benefits of treatment for those with pure systolic hypertension precludes any recommendations in regard to pharmacologic treatment of this condition.",
author = "Dyer, {A. R.} and J. Stamler and Shekelle, {R. B.} and Schoenberger, {J. A.} and E. Farinaro",
note = "Funding Information: It is a pleasure to acknowledge the cooperation of the authors' senior colleagues in the long-term investigations presented here: especially Howard Adler, Ph.D., David M. Berkson, M.D., Morton B. Epstein, Ph.D., Howard A. Lindberg, M.D., Rose Stamler, M.A. The authors are also most grateful to the group of research assistants, programmers, technicians, clerks and secretaries who have contributed so vitally to the research over the years-particularly Roberta Crawford, Nancy Dalton, Wand a Drake, Celene Epstein, Dan Garside, Dana King, William H. McAtee, Wilda Miller, Frances Petersen, Margie Shores, Elizabeth Stevens, Tom Tokich, Ika Tomaschewsky and Julia Wannamaker. The authors are also indebted to those individuals who worked on the Chicago Stroke Study. It is also a pleasure to express appreciation to the many Chicago organizations and their staffs giving invaluable cooperation in the cited research efforts, particularly the Chicago Board of Health and its Division of Adult Health and Aging, the Chicago Health Research Foundation, the Chicago Heart Association and its Detection Project in Industry, and the Peoples Gas Light and Coke Company. The authors are also most grateful to the Principal Investigators of the prospective studies of Albany civil servants, Chicago Western Electric Company employees, Framingham community residents, Los Angeles civil servants, and Minneapolis-St. Paul business and professional men, and to the coordinators of the national cooperative Pooling Project. It is a pleasure to acknowledge the cooperation and aid of our colleagues in this endeavor, Drs. Henry Blackburn, John M. Chapman, Thomas R. Dawber, Joseph T. Doyle, Frederick H. Epstein, William B. Kannel, Ancel Keys, Felix J. Moore, Oglesby Paul and Henry L. Taylor. Appreciation is also expressed to the following colleagues and publishers for permission to cite from published works: Drs. E. Freis and W. B. Kannel; Journal of the American Medical Association, Circulation. The authors' research reported here has been supported by the American Heart Association; Chicago Heart Association; Illinois Regional Medical Program; and the National Heart and Lung Institute, National Institutes of Health, United States Public Health Service. This paper was written while Alan R. Dyer was an Established Investigator of the American Heart Association.",
year = "1977",
doi = "10.1016/S0025-7125(16)31314-1",
language = "English (US)",
volume = "61",
pages = "513--529",
journal = "Unknown Journal",
issn = "0891-5849",
publisher = "Elsevier Inc.",
number = "3",
}