Hyponatremia in heart failure

Dimitrios Farmakis, Gerasimos Filippatos*, John Parissis, Dimitrios Th Kremastinos, Mihai Gheorghiade

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

60 Scopus citations


Hyponatremia is the most common electrolyte abnormality found in hospitalized patients with heart failure. It may occur in patients who have hypovolemic, hypervolemic, or euvolemic state. It is usually not corrected by available therapies. It is a major predictor of prognosis, and correction of hyponatremia can be effectively accomplished by vasopressin antagonists. However, it still remains to be seen whether the normalization of serum sodium with vasopressin antagonists will also lead to an improved long-term prognosis.

Original languageEnglish (US)
Pages (from-to)59-63
Number of pages5
JournalHeart Failure Reviews
Issue number2
StatePublished - 2009


  • Conivaptan
  • Heart failure
  • Hyponatremia
  • Lixivaptan
  • Tolvaptan
  • Vasopressin

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine


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