Hyponatremia in patients with heart failure.

Leonardo De Luca*, Liviu Klein, James E. Udelson, Cesare Orlandi, Gennaro Sardella, Francesco Fedele, Mihai Gheorghiade

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

59 Scopus citations


Mild hyponatremia is encountered frequently in patients hospitalized for worsening heart failure. Admission plasma sodium concentration appears to be an independent predictor of increased mortality after discharge and rehospitalization. Recent studies have suggested that correction of hyponatremia may be associated with improved survival. This hypothesis is currently being studied in large prospective randomized clinical trials.

Original languageEnglish (US)
Pages (from-to)19-23
Number of pages5
JournalThe American Journal of Cardiology
Issue number12 A
StatePublished - Jan 1 2005

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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