Hyponatremia in the Neurologically Ill Patient: A Review

David P. Lerner, Starane A. Shepherd, Ayush Batra*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

4 Scopus citations


Hyponatremia is a well-known disorder commonly faced by clinicians managing neurologically ill patients. Neurological disorders are often associated with hyponatremia during their acute presentation and can be associated with specific neurologic etiologies and symptoms. Patients may present with hyponatremia with traumatic brain injury, develop hyponatremia subacutely following aneurysmal subarachnoid hemorrhage, or may manifest with seizures due to hyponatremia itself. Clinicians caring for the neurologically ill patient should be well versed in identifying these early signs, symptoms, and etiologies of hyponatremia. Early diagnosis and treatment can potentially avoid neurologic and systemic complications in these patients and improve outcomes. This review focuses on the causes and findings of hyponatremia in the neurologically ill patient and discusses the pathophysiology, diagnoses, and treatment strategies for commonly encountered etiologies.

Original languageEnglish (US)
Pages (from-to)208-216
Number of pages9
Issue number3
StatePublished - Jul 1 2020


  • cerebral salt wasting
  • encephalopathy
  • hyponatremia
  • sodium

ASJC Scopus subject areas

  • Clinical Neurology


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