Hypoplasia of hemispheric white matter, peculiar pallidal changes and dysplastic inferior olives in a child with psychomotor retardation

Dikran S. Horoupian*, Mauro Dal Canto, Isabelle Rapin

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

A 25-month-old child with nonprogressive psychomotor retardation is described. Symmetrical hypoplasia of hemispheric white matter with an apparently intact cortex was a major finding. Maternal trauma to abdomen at 25 weeks of gestation was probably implicated in precipitating the condition. Also, changes resembling hypertrophy of the inferior olives were found in the pallida and were associated with dysplasia of the inferior olivary nuclei. There were other findings to suggest that the pallidal and olivary changes were secondary to deafferentation.

Original languageEnglish (US)
Pages (from-to)191-195
Number of pages5
JournalActa Neuropathologica
Volume42
Issue number3
DOIs
StatePublished - Jan 1 1978

Keywords

  • Deafferentation
  • Dysplastic inferior olivary nuclei
  • Pallidal changes
  • Perinatal brain damage
  • Psychomotor retardation
  • White matter hypoplasia

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Clinical Neurology
  • Cellular and Molecular Neuroscience

Fingerprint Dive into the research topics of 'Hypoplasia of hemispheric white matter, peculiar pallidal changes and dysplastic inferior olives in a child with psychomotor retardation'. Together they form a unique fingerprint.

Cite this