Hypothalamic–pituitary–adrenal axis dysfunction in non-clinical psychosis

Vijay Anand Mittal; Joseph Michael Orr; Andrea Pelletier; Derek James Dean; Ashley Smith; Jessica Lunsford-Avery

doi:10.1016/j.psychres.2012.12.021

Hypothalamic–pituitary–adrenal axis dysfunction in non-clinical psychosis

Vijay Anand Mittal^*, Joseph Michael Orr, Andrea Pelletier, Derek James Dean, Ashley Smith, Jessica Lunsford-Avery

^*Corresponding author for this work

Psychology

Research output: Contribution to journal › Article › peer-review

15 Scopus citations

Abstract

While studies have examined psychosocial stress in non-clinical psychosis (NCP), it is unclear if the elevated cortisol seen in schizophrenia also occurs in this group. Cortisol was sampled in High- and Low-NCP groups, and findings of elevated resting cortisol in the former suggest that hypothalamic–pituitary–adrenal-axis dysfunction underlies a psychosis continuum.

Original language	English (US)
Pages (from-to)	315-317
Number of pages	3
Journal	Psychiatry Research
Volume	206
Issue number	2-3
DOIs	https://doi.org/10.1016/j.psychres.2012.12.021
State	Published - Apr 30 2013

Keywords

Cortisol
Hypothalamic–pituitary–adrenal axis
Non-clinical psychosis

ASJC Scopus subject areas

Psychiatry and Mental health
Biological Psychiatry

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.psychres.2012.12.021

Cite this

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title = "Hypothalamic–pituitary–adrenal axis dysfunction in non-clinical psychosis",

abstract = "While studies have examined psychosocial stress in non-clinical psychosis (NCP), it is unclear if the elevated cortisol seen in schizophrenia also occurs in this group. Cortisol was sampled in High- and Low-NCP groups, and findings of elevated resting cortisol in the former suggest that hypothalamic–pituitary–adrenal-axis dysfunction underlies a psychosis continuum.",

keywords = "Cortisol, Hypothalamic–pituitary–adrenal axis, Non-clinical psychosis",

author = "Mittal, {Vijay Anand} and Orr, {Joseph Michael} and Andrea Pelletier and Dean, {Derek James} and Ashley Smith and Jessica Lunsford-Avery",

note = "Funding Information: There are no potential conflicts of interest to report. This work was supported by the National Institute of Health Grant nos. R01MH094650 and MH087258 to Dr. Mittal. Publisher Copyright: {\textcopyright} 2012 Elsevier Ireland Ltd",

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T1 - Hypothalamic–pituitary–adrenal axis dysfunction in non-clinical psychosis

AU - Mittal, Vijay Anand

AU - Orr, Joseph Michael

AU - Pelletier, Andrea

AU - Dean, Derek James

AU - Smith, Ashley

AU - Lunsford-Avery, Jessica

N1 - Funding Information: There are no potential conflicts of interest to report. This work was supported by the National Institute of Health Grant nos. R01MH094650 and MH087258 to Dr. Mittal. Publisher Copyright: © 2012 Elsevier Ireland Ltd

PY - 2013/4/30

Y1 - 2013/4/30

N2 - While studies have examined psychosocial stress in non-clinical psychosis (NCP), it is unclear if the elevated cortisol seen in schizophrenia also occurs in this group. Cortisol was sampled in High- and Low-NCP groups, and findings of elevated resting cortisol in the former suggest that hypothalamic–pituitary–adrenal-axis dysfunction underlies a psychosis continuum.

AB - While studies have examined psychosocial stress in non-clinical psychosis (NCP), it is unclear if the elevated cortisol seen in schizophrenia also occurs in this group. Cortisol was sampled in High- and Low-NCP groups, and findings of elevated resting cortisol in the former suggest that hypothalamic–pituitary–adrenal-axis dysfunction underlies a psychosis continuum.

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KW - Hypothalamic–pituitary–adrenal axis

KW - Non-clinical psychosis

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JF - Psychiatry Research

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ER -

Hypothalamic–pituitary–adrenal axis dysfunction in non-clinical psychosis

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

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