Hypothermia: Application and Use in Neurocritical Care

Edward M. Manno*

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingChapter


The application of hypothermia to prevent neurological damage is an old concept which has reached prominence after two randomized trials revealed significant improvements in neurological outcome after cardiac arrest from ventricular fibrillation. Significant questions remain as to the timing and duration of its application. Similarly, limited information on neurological prognostication after hypothermic cardiac arrest currently exists. The expansion of therapeutic hypothermia to other neurological diseases has not proved beneficial. Continued research in the clinical application of this modality is needed.

Original languageEnglish (US)
Title of host publicationEmergency Management in Neurocritical Care
Number of pages9
ISBN (Electronic)9781118297162
ISBN (Print)9780470654736
StatePublished - Jan 1 2013


  • Brain injury
  • Hypothermia
  • Shivering
  • Therapeutic hypothermia

ASJC Scopus subject areas

  • General Medicine


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