TY - JOUR
T1 - Identification of phenotypic patterns of dysphagia
T2 - A proof of concept study
AU - Focht Garand, Kendrea L.
AU - Armeson, Kent E.
AU - Hill, Elizabeth G.
AU - Martin-Harris, Bonnie
N1 - Funding Information:
The contents of this publication were developed under grants from the National Institutes of Health under Grant K23DC005764 (PI: Martin-Harris) and Grant 1K24DC12801 (PI: Martin-Harris).
Publisher Copyright:
© 2018 American Speech-Language-Hearing Association.
PY - 2018/8
Y1 - 2018/8
N2 - Purpose: The purpose of the current project was to explore the feasibility for subtyping dysphagia traits or patterns of scores in a subset of data from the Modified Barium Swallow Impairment Profile global registry in patients referred to videofluoroscopic swallowing studies across 5 common medical categories: (a) cardiothoracic, (b) gastroenterology, (c) head and neck cancer, (d) neurology, and (e) pulmonary. Method: Videofluoroscopic swallowing study imaging and Modified Barium Swallow Impairment Profile metrics were used to evaluate 235 patients with dysphagia grouped into 1 of the 5 categories. Two summative domain scores (oral total [OT] and pharyngeal total [PT]) and 17 component scores were tested for differences among the categories. Results: When compared with the gastroenterology category, significantly higher OT/PT scores were observed in neurology and pulmonary categories (all p values <.05). Four oral and 6 pharyngeal domain components significantly differed across medical categories: tongue control during bolus hold (all p values <.04). Conclusions: The results of this feasibility study demonstrate that summative scores of swallowing physiology alone are not sufficiently robust to distinguish subtypes of dysphagia in broad, heterogeneous medical categories. Using OT/PT as subtypes only separated gastroenterology from the other categories, suggesting overlap in OT/PT scores between the latter categories.
AB - Purpose: The purpose of the current project was to explore the feasibility for subtyping dysphagia traits or patterns of scores in a subset of data from the Modified Barium Swallow Impairment Profile global registry in patients referred to videofluoroscopic swallowing studies across 5 common medical categories: (a) cardiothoracic, (b) gastroenterology, (c) head and neck cancer, (d) neurology, and (e) pulmonary. Method: Videofluoroscopic swallowing study imaging and Modified Barium Swallow Impairment Profile metrics were used to evaluate 235 patients with dysphagia grouped into 1 of the 5 categories. Two summative domain scores (oral total [OT] and pharyngeal total [PT]) and 17 component scores were tested for differences among the categories. Results: When compared with the gastroenterology category, significantly higher OT/PT scores were observed in neurology and pulmonary categories (all p values <.05). Four oral and 6 pharyngeal domain components significantly differed across medical categories: tongue control during bolus hold (all p values <.04). Conclusions: The results of this feasibility study demonstrate that summative scores of swallowing physiology alone are not sufficiently robust to distinguish subtypes of dysphagia in broad, heterogeneous medical categories. Using OT/PT as subtypes only separated gastroenterology from the other categories, suggesting overlap in OT/PT scores between the latter categories.
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U2 - 10.1044/2018_AJSLP-17-0173
DO - 10.1044/2018_AJSLP-17-0173
M3 - Article
C2 - 29800022
AN - SCOPUS:85051400440
VL - 27
SP - 988
EP - 995
JO - American Journal of Speech-Language Pathology
JF - American Journal of Speech-Language Pathology
SN - 1058-0360
IS - 3
ER -