Identifying the reproductive toxicity of biocompatible 3d-printed dental resins

Hunter B. Rogers, Emily Zaniker, Luhan Zhou, Atsuko Kusuhara, Francesca Elizabeth Duncan, Teresa K Woodruff

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

With the development of more sophisticated manufacturing techniques, biomaterials are increasingly being developed and used in biomedical research, including in reproductive science and medicine. One aspect of new biomaterials that is often overlooked is the potential for adverse effects on reproductive health, such as gamete development and quality. Biomaterials frequently contain plastics or leachates that may appear to be biocompatible with respect to non-reproductive tissues but are later found to exhibit reproductive toxicity. As 3D-printing has become more accessible and printers have become more advanced, 3D-printing technology is a promising resource for the creation of new biomedical devices. However, the resins currently available for most printers are still limited, with only a few that have been tested for their biocompatibility. The objective of this study was to test the potential reproductive toxicity of two commercially available 3D-printable dental resins that are currently marketed as biocompatible: Dental SG (DSG) and Dental LT (DLT). DSG is a Class I certified biocompatible material meant for printing custom surgical guides. DLT is a Class IIa certified biocompatible material that is designed for printing oral retainers, and therefore extended human contact.

Original languageEnglish (US)
Title of host publicationSociety for Biomaterials Annual Meeting and Exposition 2019
Subtitle of host publicationThe Pinnacle of Biomaterials Innovation and Excellence - Transactions of the 42nd Annual Meeting
PublisherSociety for Biomaterials
Number of pages1
ISBN (Electronic)9781510883901
StatePublished - Jan 1 2019
Event42nd Society for Biomaterials Annual Meeting and Exposition 2019: The Pinnacle of Biomaterials Innovation and Excellence - Seattle, United States
Duration: Apr 3 2019Apr 6 2019

Publication series

NameTransactions of the Annual Meeting of the Society for Biomaterials and the Annual International Biomaterials Symposium
Volume40
ISSN (Print)1526-7547

Conference

Conference42nd Society for Biomaterials Annual Meeting and Exposition 2019: The Pinnacle of Biomaterials Innovation and Excellence
CountryUnited States
CitySeattle
Period4/3/194/6/19

ASJC Scopus subject areas

  • Biochemistry
  • Biophysics
  • Biotechnology
  • Biomaterials
  • Materials Chemistry

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