Idiopathic anaphylaxis

Anne Marie Ditto*, Anjeni Keswani

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingChapter


Idiopathic anaphylaxis is defined as recurrent episodes of anaphylaxis without a known trigger. It is a diagnosis of exclusion after triggers such as foods, medications or insect stings and diseases that mimic anaphylaxis are ruled out. The pathophysiology of idiopathic anaphylaxis is still unknown and thus, the mechanism is under investigation. Idiopathic anaphylaxis is classified according to the constellation of symptoms and frequency of episodes. It can then be treated with 'triple therapy' of epinephrine, steroids, and antihistamines for acute attacks and a regimen of remittive therapy, consisting of steroids and antihistamines, for those patients with frequent episodes. The prognosis of idiopathic anaphylaxis is favorable if it is recognized and appropriately treated.

Original languageEnglish (US)
Title of host publicationAnaphylaxis - Principles and Practice
PublisherNova Science Publishers, Inc.
Number of pages24
ISBN (Print)9781626186880
StatePublished - 2013

ASJC Scopus subject areas

  • Medicine(all)


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