TY - JOUR
T1 - Idiopathic Anaphylaxis
AU - Greenberger, Paul A.
N1 - Funding Information:
Supported by the Ernest S. Bazley Grant to Northwestern Memorial Hospital and Northwestern University.
PY - 2007/5
Y1 - 2007/5
N2 - Idiopathic anaphylaxis is a prednisone-responsive condition without external cause, but it can coexist with food-, medication-, or exercise-induced anaphylaxis. Mast cell activation may occur at night or after foods that have been eaten with impunity many times previously. Idiopathic anaphylaxis can be classified into frequent (if there are six or more episodes per year or two episodes in the last 2 months) or infrequent (if episodes occur less often). Idiopathic anaphylaxis-generalized consists of urticaria or angioedema associated with severe respiratory distress, syncope or hypotension, and gastrointestinal symptoms. Idiopathic anaphylaxis-angioedema consists of massive tongue enlargement or severe pharyngeal or laryngeal swelling with urticaria or peripheral angioedema. The differential diagnosis of idiopathic anaphylaxis is reviewed, and treatment approaches are presented.
AB - Idiopathic anaphylaxis is a prednisone-responsive condition without external cause, but it can coexist with food-, medication-, or exercise-induced anaphylaxis. Mast cell activation may occur at night or after foods that have been eaten with impunity many times previously. Idiopathic anaphylaxis can be classified into frequent (if there are six or more episodes per year or two episodes in the last 2 months) or infrequent (if episodes occur less often). Idiopathic anaphylaxis-generalized consists of urticaria or angioedema associated with severe respiratory distress, syncope or hypotension, and gastrointestinal symptoms. Idiopathic anaphylaxis-angioedema consists of massive tongue enlargement or severe pharyngeal or laryngeal swelling with urticaria or peripheral angioedema. The differential diagnosis of idiopathic anaphylaxis is reviewed, and treatment approaches are presented.
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U2 - 10.1016/j.iac.2007.03.009
DO - 10.1016/j.iac.2007.03.009
M3 - Review article
C2 - 17493503
AN - SCOPUS:34247572369
VL - 27
SP - 273
EP - 293
JO - Immunology and Allergy Clinics of North America
JF - Immunology and Allergy Clinics of North America
SN - 0889-8561
IS - 2
ER -