Idiopathic anaphylaxis

Karen Hsu Blatman*, Leslie C. Grammer

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations


When anaphylaxis occurs in the absence of an identifiable trigger, the anaphylactic reaction is termed idiopathic. It is a well-described type of anaphylaxis with treatment that is associated with good prognosis. Episodes may be reduced with prophylactic corticosteroids and antihistamines. There is no definitive diagnostic test for idiopathic anaphylaxis. By definition, it is a diagnosis of exclusion after eliminating other causes. Disorders that may mimic anaphylaxis should be considered for evaluation. The cause of idiopathic anaphylaxis remains uncertain.

Original languageEnglish (US)
Title of host publicationAnaphylaxis and Hypersensitivity Reactions
PublisherHumana Press
Number of pages12
ISBN (Print)9781603279505
StatePublished - 2011


  • Anaphylaxis
  • Angioedema
  • Aspirin
  • Bee pollen
  • C-kit
  • Carcinoid
  • Clonal mast cell
  • Corticosteroids
  • Doxepin
  • Exercise-induced anaphylaxis
  • Histamine
  • Histamine-releasing factor
  • Hydatid cyst disease
  • Idiopathic anaphylaxis
  • Ketotifen
  • Latex hypersensitivity
  • Leukotriene D4
  • Mast cells
  • Mastocytosis
  • Mite-contaminated flour
  • Montelukast
  • Munchausen stridor
  • Omalizumab
  • Oral albuterol
  • Oral cromolyn
  • Pheochromocytoma
  • Progesterone
  • Scrombroidosis
  • Tryptase
  • Undifferentiated somatoform anaphylaxis
  • Urticaria
  • Vocal cord dysfunction

ASJC Scopus subject areas

  • Medicine(all)

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