Idiopathic childhood stroke is associated with human leukocyte antigen (HLA)–B51

Mark Mintz*, Leon G. Epstein, M. Richard Koenigsberger

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

20 Scopus citations

Abstract

We report four children with idiopathic stroke syndromes who were assayed for human leukocyte antigen (HLA) class I markers and found to have HLA‐B51 in common. This finding suggests that may be a genetic predisposition for “idiopathic” childhood stroke, and host factors, possibly in concert with environmental factors or viruses, may play a major role in the mechanism of unexplained occlusion of the cerebral vasculature in children.

Original languageEnglish (US)
Pages (from-to)675-677
Number of pages3
JournalAnnals of Neurology
Volume31
Issue number6
DOIs
StatePublished - Jan 1 1992

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology

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