Idiopathic childhood stroke is associated with human leukocyte antigen (HLA)–B51

Mark Mintz; Leon G. Epstein; M. Richard Koenigsberger

doi:10.1002/ana.410310618

Idiopathic childhood stroke is associated with human leukocyte antigen (HLA)–B51

Mark Mintz^*, Leon G. Epstein, M. Richard Koenigsberger

^*Corresponding author for this work

Pediatrics

Research output: Contribution to journal › Article › peer-review

22 Scopus citations

Abstract

We report four children with idiopathic stroke syndromes who were assayed for human leukocyte antigen (HLA) class I markers and found to have HLA‐B51 in common. This finding suggests that may be a genetic predisposition for “idiopathic” childhood stroke, and host factors, possibly in concert with environmental factors or viruses, may play a major role in the mechanism of unexplained occlusion of the cerebral vasculature in children.

Original language	English (US)
Pages (from-to)	675-677
Number of pages	3
Journal	Annals of neurology
Volume	31
Issue number	6
DOIs	https://doi.org/10.1002/ana.410310618
State	Published - Jun 1992

ASJC Scopus subject areas

Clinical Neurology
Neurology

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10.1002/ana.410310618

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title = "Idiopathic childhood stroke is associated with human leukocyte antigen (HLA)–B51",

abstract = "We report four children with idiopathic stroke syndromes who were assayed for human leukocyte antigen (HLA) class I markers and found to have HLA‐B51 in common. This finding suggests that may be a genetic predisposition for “idiopathic” childhood stroke, and host factors, possibly in concert with environmental factors or viruses, may play a major role in the mechanism of unexplained occlusion of the cerebral vasculature in children.",

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N2 - We report four children with idiopathic stroke syndromes who were assayed for human leukocyte antigen (HLA) class I markers and found to have HLA‐B51 in common. This finding suggests that may be a genetic predisposition for “idiopathic” childhood stroke, and host factors, possibly in concert with environmental factors or viruses, may play a major role in the mechanism of unexplained occlusion of the cerebral vasculature in children.

AB - We report four children with idiopathic stroke syndromes who were assayed for human leukocyte antigen (HLA) class I markers and found to have HLA‐B51 in common. This finding suggests that may be a genetic predisposition for “idiopathic” childhood stroke, and host factors, possibly in concert with environmental factors or viruses, may play a major role in the mechanism of unexplained occlusion of the cerebral vasculature in children.

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Idiopathic childhood stroke is associated with human leukocyte antigen (HLA)–B51

Abstract

ASJC Scopus subject areas

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