Idiosyncratic drug-induced liver injury: A clinical update

Haripriya Maddur, Naga Chalasani*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

15 Scopus citations


Drug-induced liver injury (DILI) is a rare but potentially devastating adverse drug reaction. Its presentation can range from asymptomatic elevation in liver biochemistries to fulminant liver failure. Over the past decade, clinical and research interest in the field of idiosyncratic DILI has been intense, and several new findings have been reported. In this article, we provide an update on implicated agents, clinical features, outcomes, and the results of recently reported genetic studies.

Original languageEnglish (US)
Pages (from-to)65-71
Number of pages7
JournalCurrent gastroenterology reports
Issue number1
StatePublished - Feb 1 2011


  • Drug-Induced Liver Injury Network (DILIN)
  • Drug-induced liver injury (DILI)
  • Genome-wide association studies

ASJC Scopus subject areas

  • Gastroenterology

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