Illness intrusiveness explains race-related quality-of-life differences among women with systemic lupus erythematosus

ARAMIS Lupus State Models Research Group

Research output: Contribution to journalArticlepeer-review

39 Scopus citations

Abstract

Our objective was to investigate whether quality of life in systemic lupus erythematosus (SLE) differs across ethnoracial groups and to identify factors that may explain race-related differences. Self-administered questionnaire data from 335 White, 40 Black, and 30 Asian women with SLE were obtained from a multi-center database. Measures assessed illness intrusiveness, psychological well-being, depressive symptoms, musculoskeletal pain, and learned helplessness. Extent of SLE disease activity was indexed by self-reported functional-system involvement. Educational attainment was indicated by number of years in school. Principal-components analysis reduced the four psychosocial measures to a single factor score. This represented psychosocial well-being in path analysis. Psychosocial well-being differed significantly across the three groups, with Whites reporting the highest, and Blacks the lowest, levels. Path analysis indicated that illness intrusiveness accounted for this race-related difference. Although disease activity was significantly associated with psychosocial well-being, it did not differ across ethnoracial groups. Illness intrusiveness and educational attainment emerged as independent mediators of the race-related difference in psychosocial well-being. We conclude that race-related quality-of-life differences exist among women with SLE and are mediated independently by illness intrusiveness and educational attainment.

Original languageEnglish (US)
Pages (from-to)534-541
Number of pages8
JournalLupus
Volume9
Issue number7
DOIs
StatePublished - 2000

Keywords

  • Psychosocial
  • Quality of life
  • Race
  • Systemic lupus erythematosus

ASJC Scopus subject areas

  • Rheumatology

Fingerprint Dive into the research topics of 'Illness intrusiveness explains race-related quality-of-life differences among women with systemic lupus erythematosus'. Together they form a unique fingerprint.

Cite this