Image-guided frameless stereotactic biopsy sampling of parasellar lesions: Technical note

Leonardo Frighetto, Antonio A F De Salles, Eric Behnke, Zachary A. Smith, Dennis Chute

Research output: Contribution to journalArticlepeer-review

22 Scopus citations


Interactive image-guided neuronavigation was used to obtain biopsy specimens of cavernous sinus (CS) tumors via the foramen ovale. In this study the authors demonstrated a minimally invasive approach in the management of these lesions. In four patients, whose ages ranged from 29 to 89 years (mean 61.2 years) and who harbored undefined lesions invading the CS, neuronavigation was used to perform frameless stereotactic fine-needle biopsy sampling through the foramen ovale. The biopsy site was confirmed on postoperative computerized tomography scanning. The frameless technique was accurate in displaying a real-time trajectory of the biopsy needle throughout the procedure. The lesions within the CS were approached precisely and safely. Diagnostic tissue was obtained in all cases and treatment was administered with the aid of stereotactic radiosurgery or fractionated stereotactic radiotherapy. The patients were discharged after an overnight stay with no complications. Neuronavigation is a precise and useful tool for image-guided biopsy sampling of CS tumors via the foramen ovale.

Original languageEnglish (US)
Pages (from-to)920-925
Number of pages6
JournalJournal of neurosurgery
Issue number4
StatePublished - Apr 1 2003


  • Cavernous sinus
  • Image-guided surgery
  • Needle biopsy
  • Neuronavigation
  • Stereotaxy

ASJC Scopus subject areas

  • Surgery
  • Clinical Neurology


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