Imaging of HIV/host protein interactions

Cindy M. Danielson, Thomas J. Hope

Research output: Chapter in Book/Report/Conference proceedingChapter

5 Scopus citations

Abstract

HIV-1 relies on a myriad of interactions with host cell proteins to carry out its life cycle. Traditional biochemical approaches to probe protein-protein interactions are limited in their ability to study the spatial and dynamic interactions that take place in the context of an intact cell. However, issues such as localization and dynamics of interactions between viral and host proteins can be well addressed utilizing fluorescent imaging methods. The past decade has brought about the development of many novel fluorescent imaging techniques which have proved useful to describe the interaction of HIV-1 proteins with the host cell.

Original languageEnglish (US)
Title of host publicationHIV Interactions with Host Cell Proteins
EditorsPaul Spearman, Eric Freed
Pages103-123
Number of pages21
Edition1
DOIs
StatePublished - Dec 1 2009

Publication series

NameCurrent Topics in Microbiology and Immunology
Number1
Volume339
ISSN (Print)0070-217X

ASJC Scopus subject areas

  • Immunology and Allergy
  • Microbiology
  • Immunology
  • Microbiology (medical)

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  • Cite this

    Danielson, C. M., & Hope, T. J. (2009). Imaging of HIV/host protein interactions. In P. Spearman, & E. Freed (Eds.), HIV Interactions with Host Cell Proteins (1 ed., pp. 103-123). (Current Topics in Microbiology and Immunology; Vol. 339, No. 1). https://doi.org/10.1007/978-3-642-02175-6-6