Immune-related genetic enrichment in frontotemporal dementia: An analysis of genome-wide association studies

Keyphrases

• Genome-wide Association Study 100%
• Frontotemporal Dementia 100%
• Immune-related 100%
• Genome Enrichment 100%
• Rheumatoid Arthritis 23%
• Immune-mediated Diseases 23%
• Human Leukocyte Antigen 23%
• Amyotrophic Lateral Sclerosis 17%
• Progressive Supranuclear Palsy 17%
• Celiac Disease 17%
• Corticobasal Degeneration 17%
• Type 1 Diabetes Mellitus (T1DM) 11%
• Single nucleotide Polymorphism 11%
• Immune Response 11%
• Ulcerative Colitis 11%
• Immune Dysfunction 11%
• Type I Diabetes 11%
• Dementia Risk 11%
• Chromosome 6 11%
• Genetic Overlap 11%
• Clinical Trials 5%
• Susceptibility Loci 5%
• Linkage Disequilibrium 5%
• Macrophages 5%
• Psoriasis 5%
• Specific Genes 5%
• Genetic Studies 5%
• Postmortem Tissue 5%
• Microglia 5%
• Binding Protein 5%
• Transposable Elements 5%
• Related Disorders 5%
• Central Nervous System Cells 5%
• Dementia Diseases 5%
• Degenerative Disease 5%
• Fold Enrichment 5%
• Leucine-rich Repeat Kinase 2 (LRRK2) 5%
• Crohn's Disease 5%
• Genetic Results 5%
• OR Genes 5%
• Dementia with 5%
• TANK-binding Kinase 1 (TBK1) 5%
• Large Genome 5%
• Converging Evidence 5%
• False Discovery Rate 5%
• Pleiotropy 5%
• PiggyBac 5%
• Pleiotropic Gene 5%

Neuroscience

• Frontotemporal Dementia 100%
• Genome-Wide Association Study 100%
• Rheumatoid Arthritis 23%
• Human Leukocyte Antigen 23%
• Amyotrophic Lateral Sclerosis 17%
• Progressive Supranuclear Palsy 17%
• Corticobasal Degeneration 17%
• Immune System Disorders 11%
• Chromosome 6 11%
• Single-Nucleotide Polymorphism 11%
• Nervous System Cell 5%
• Central Nervous System 5%
• Linkage Disequilibrium 5%
• False Discovery Rate 5%
• Macrophage 5%
• Protein Binding 5%
• Synapsin I 5%
• Leucine Rich Repeat Kinase 2 5%
• Microglia 5%
• Transposon 5%

Biochemistry, Genetics and Molecular Biology

• Genetics 100%
• Genome-Wide Association Study 100%
• Human Leukocyte Antigen 33%
• Single-Nucleotide Polymorphism 16%
• Chromosome 6 16%
• Pleiotropy 8%
• Binding Protein 8%
• Transposable Element 8%
• Leucine-Rich Repeat 8%
• Clinical Trial 8%
• Macrophage 8%
• Gene Linkage Disequilibrium 8%
• Kinase 8%
• Phosphotransferase 8%
• Microglia 8%
• Synapsin I 8%