Immunodeficiency syndromes: X-linked agammaglobulinemia, common variable immunodeficiency, Chediak-Higashi syndrome, Wiskott-Aldrich syndrome, and X- linked lymphoproliferative disorder

A. S. Paller*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

9 Scopus citations

Abstract

The incidence and mortality of neoplasia in patients with primary immunodeficiencies exceed the anticipated rates in the normal population by approximately 100 to 300 times. Lymphoreticular malignancies account for the majority of tumors, although solid tumors, especially gastric carcinoma, occur with increased frequency as well. More than half of these neoplasms are diagnosed by ten years of age, except in patients with a later age of onset of immunodeficiency. Five primary immunodeficiency disorders with an increased risk of neoplasia are reviewed.

Original languageEnglish (US)
Pages (from-to)65-71
Number of pages7
JournalDermatologic clinics
Volume13
Issue number1
StatePublished - Jan 1 1995

ASJC Scopus subject areas

  • Dermatology

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