Immunohistochemical localization of human growth hormone-like material in the median eminence of the rat: Light and electron microscopic observations

Ronald M. Lechan; Joan C. King; Mark E. Molitch; Jeffrey Aalberg

doi:10.1016/0304-3940(82)90404-9

Immunohistochemical localization of human growth hormone-like material in the median eminence of the rat: Light and electron microscopic observations

Ronald M. Lechan^*, Joan C. King, Mark E. Molitch, Jeffrey Aalberg

^*Corresponding author for this work

Medicine, Endocrinology Division

Research output: Contribution to journal › Article › peer-review

5 Scopus citations

Abstract

Usng the peroxidase-antipoeroxidase pre-embedding technique for immunoelectron microscopy, human growth hormone (hGH)-like material was demonstrated in large, dense core vesicles in axon terminals in the hypothalamic median eminence of the rat. The close association of immunoreactive terminals with fenestrated capillaries of the portal plexus, suggests that the hGH-like material is contained within the tuberoinfundibular neuronal system and may be a hypophysiotropic hormone.

Original language	English (US)
Pages (from-to)	229-234
Number of pages	6
Journal	Neuroscience Letters
Volume	30
Issue number	3
DOIs	https://doi.org/10.1016/0304-3940(82)90404-9
State	Published - Jun 30 1982

Keywords

electron microscopy
human growth hormone-like material
immunohistochemistry
portal capillaries
rat
tuberoinfundibular system

ASJC Scopus subject areas

General Neuroscience

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10.1016/0304-3940(82)90404-9

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title = "Immunohistochemical localization of human growth hormone-like material in the median eminence of the rat: Light and electron microscopic observations",

abstract = "Usng the peroxidase-antipoeroxidase pre-embedding technique for immunoelectron microscopy, human growth hormone (hGH)-like material was demonstrated in large, dense core vesicles in axon terminals in the hypothalamic median eminence of the rat. The close association of immunoreactive terminals with fenestrated capillaries of the portal plexus, suggests that the hGH-like material is contained within the tuberoinfundibular neuronal system and may be a hypophysiotropic hormone.",

keywords = "electron microscopy, human growth hormone-like material, immunohistochemistry, portal capillaries, rat, tuberoinfundibular system",

author = "Lechan, {Ronald M.} and King, {Joan C.} and Molitch, {Mark E.} and Jeffrey Aalberg",

year = "1982",

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doi = "10.1016/0304-3940(82)90404-9",

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T1 - Immunohistochemical localization of human growth hormone-like material in the median eminence of the rat

T2 - Light and electron microscopic observations

AU - Lechan, Ronald M.

AU - King, Joan C.

AU - Molitch, Mark E.

AU - Aalberg, Jeffrey

PY - 1982/6/30

Y1 - 1982/6/30

N2 - Usng the peroxidase-antipoeroxidase pre-embedding technique for immunoelectron microscopy, human growth hormone (hGH)-like material was demonstrated in large, dense core vesicles in axon terminals in the hypothalamic median eminence of the rat. The close association of immunoreactive terminals with fenestrated capillaries of the portal plexus, suggests that the hGH-like material is contained within the tuberoinfundibular neuronal system and may be a hypophysiotropic hormone.

AB - Usng the peroxidase-antipoeroxidase pre-embedding technique for immunoelectron microscopy, human growth hormone (hGH)-like material was demonstrated in large, dense core vesicles in axon terminals in the hypothalamic median eminence of the rat. The close association of immunoreactive terminals with fenestrated capillaries of the portal plexus, suggests that the hGH-like material is contained within the tuberoinfundibular neuronal system and may be a hypophysiotropic hormone.

KW - electron microscopy

KW - human growth hormone-like material

KW - immunohistochemistry

KW - portal capillaries

KW - rat

KW - tuberoinfundibular system

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AN - SCOPUS:0019961949

SN - 0304-3940

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JO - Neuroscience Letters

JF - Neuroscience Letters

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ER -

Immunohistochemical localization of human growth hormone-like material in the median eminence of the rat: Light and electron microscopic observations

Abstract

Keywords

ASJC Scopus subject areas

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