Immunohistochemical localization of human growth hormone-like material in the median eminence of the rat: Light and electron microscopic observations

Ronald M. Lechan*, Joan C. King, Mark E. Molitch, Jeffrey Aalberg

*Corresponding author for this work

Research output: Contribution to journalArticle

5 Scopus citations

Abstract

Usng the peroxidase-antipoeroxidase pre-embedding technique for immunoelectron microscopy, human growth hormone (hGH)-like material was demonstrated in large, dense core vesicles in axon terminals in the hypothalamic median eminence of the rat. The close association of immunoreactive terminals with fenestrated capillaries of the portal plexus, suggests that the hGH-like material is contained within the tuberoinfundibular neuronal system and may be a hypophysiotropic hormone.

Original languageEnglish (US)
Pages (from-to)229-234
Number of pages6
JournalNeuroscience Letters
Volume30
Issue number3
DOIs
StatePublished - Jun 30 1982

Keywords

  • electron microscopy
  • human growth hormone-like material
  • immunohistochemistry
  • portal capillaries
  • rat
  • tuberoinfundibular system

ASJC Scopus subject areas

  • Neuroscience(all)

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