Immunological Unresponsiveness Produced in Adult Guinea Pigs by Parenteral Introduction of Minute Quantities of Hapten or Protein Antigen

Jack R. Battisto; Joshua Miller

doi:10.3181/00379727-111-27717

Immunological Unresponsiveness Produced in Adult Guinea Pigs by Parenteral Introduction of Minute Quantities of Hapten or Protein Antigen

Jack R. Battisto, Joshua Miller

Surgery, Transplant Surgery Division

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79 Scopus citations

Abstract

Delayed hypersensitivity and circulating antibody production to a hapten (picryl chloride) and to a protein antigen (bovine gamma globulin) were regularly suppressed in mature guinea pigs injected twice into mesenteric veins prior to sensitization, with hapten or protein in gamma amounts.

Original language	English (US)
Pages (from-to)	111-115
Number of pages	5
Journal	Proceedings of the Society for Experimental Biology and Medicine
Volume	111
Issue number	1
DOIs	https://doi.org/10.3181/00379727-111-27717
State	Published - Oct 1962

ASJC Scopus subject areas

Biochemistry, Genetics and Molecular Biology(all)

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title = "Immunological Unresponsiveness Produced in Adult Guinea Pigs by Parenteral Introduction of Minute Quantities of Hapten or Protein Antigen",

abstract = "Delayed hypersensitivity and circulating antibody production to a hapten (picryl chloride) and to a protein antigen (bovine gamma globulin) were regularly suppressed in mature guinea pigs injected twice into mesenteric veins prior to sensitization, with hapten or protein in gamma amounts.",

author = "Battisto, {Jack R.} and Joshua Miller",

year = "1962",

month = oct,

doi = "10.3181/00379727-111-27717",

language = "English (US)",

volume = "111",

pages = "111--115",

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AU - Battisto, Jack R.

AU - Miller, Joshua

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N2 - Delayed hypersensitivity and circulating antibody production to a hapten (picryl chloride) and to a protein antigen (bovine gamma globulin) were regularly suppressed in mature guinea pigs injected twice into mesenteric veins prior to sensitization, with hapten or protein in gamma amounts.

AB - Delayed hypersensitivity and circulating antibody production to a hapten (picryl chloride) and to a protein antigen (bovine gamma globulin) were regularly suppressed in mature guinea pigs injected twice into mesenteric veins prior to sensitization, with hapten or protein in gamma amounts.

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SN - 1535-3702

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EP - 115

JO - Experimental Biology and Medicine

JF - Experimental Biology and Medicine

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Immunological Unresponsiveness Produced in Adult Guinea Pigs by Parenteral Introduction of Minute Quantities of Hapten or Protein Antigen

Abstract

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