Immunological Unresponsiveness Produced in Adult Guinea Pigs by Parenteral Introduction of Minute Quantities of Hapten or Protein Antigen

Jack R. Battisto, Joshua Miller

Research output: Contribution to journalArticlepeer-review

77 Scopus citations

Abstract

Delayed hypersensitivity and circulating antibody production to a hapten (picryl chloride) and to a protein antigen (bovine gamma globulin) were regularly suppressed in mature guinea pigs injected twice into mesenteric veins prior to sensitization, with hapten or protein in gamma amounts.

Original languageEnglish (US)
Pages (from-to)111-115
Number of pages5
JournalProceedings of the Society for Experimental Biology and Medicine
Volume111
Issue number1
DOIs
StatePublished - Oct 1962

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

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