TY - JOUR
T1 - Immunosuppressive regimens in lung transplant recipients
AU - Bhorade, Sangeeta M.
AU - Villanueva, Jaime
AU - Jordan, Ashby
AU - Garrity, Edward R.
PY - 2004/12
Y1 - 2004/12
N2 - A lung transplant is usually the last resort treatment for lung failure. Since the introduction of cyclosporine A, success rates after solid organ transplantation began to rise, following an incremental curve over the last decade, in which further development of biological agents and newer immunosuppressive agents has continued to improve outcomes after transplantation. Pharmacokinetic and pharmacodynamic properties, as well as efficacy and safety data from clinical trials with immunosuppressive agents and biological agents currently available, are reviewed here.
AB - A lung transplant is usually the last resort treatment for lung failure. Since the introduction of cyclosporine A, success rates after solid organ transplantation began to rise, following an incremental curve over the last decade, in which further development of biological agents and newer immunosuppressive agents has continued to improve outcomes after transplantation. Pharmacokinetic and pharmacodynamic properties, as well as efficacy and safety data from clinical trials with immunosuppressive agents and biological agents currently available, are reviewed here.
UR - http://www.scopus.com/inward/record.url?scp=12344299578&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=12344299578&partnerID=8YFLogxK
U2 - 10.1358/dot.2004.40.12.872575
DO - 10.1358/dot.2004.40.12.872575
M3 - Review article
C2 - 15645011
AN - SCOPUS:12344299578
SN - 1699-3993
VL - 40
SP - 1003
EP - 1012
JO - Drugs of Today
JF - Drugs of Today
IS - 12
ER -
