Impact of aortopathy and aortic valve disease on 3d blood flow and wall shear stress in the thoracic aorta: As assessed by 4D flow MRI

Michael Markl; Paul W.M. Fedak; Alex Barker

doi:10.1007/978-3-7091-4874-7_29

Impact of aortopathy and aortic valve disease on 3d blood flow and wall shear stress in the thoracic aorta: As assessed by 4D flow MRI

Michael Markl^*, Paul W.M. Fedak, Alex Barker

^*Corresponding author for this work

Radiology

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

Recent advances in magnetic resonance imaging (MRI) allow for the comprehensive visualization and quantification of in vivo aortic 3D hemodynamics using 4D flow MRI. The technique offers the opportunity to derive advanced hemodynamic measures, such as wall shear stress, for an improved characterization of aortic disease beyond simple flow metrics known to be associated with aortopathy and aortic valve disease. This chapter will provide an introduction to 4D flow MRI as it is currently used for blood flow visualization and quantification of flow parameters and wall shear stress in the setting of aortopathy and aortic valve diseases with a focus on congenially abnormal bicuspid aortic valves and aortic stenosis.

Original language	English (US)
Title of host publication	Surgical Management of Aortic Pathology
Subtitle of host publication	Current Fundamentals for the Clinical Management of Aortic Disease
Publisher	Springer International Publishing
Pages	447-464
Number of pages	18
ISBN (Electronic)	9783709148747
ISBN (Print)	9783709148723
DOIs	https://doi.org/10.1007/978-3-7091-4874-7_29
State	Published - Jan 1 2019

Keywords

4D flow MRI
Aneurysm
Aorta
Aortic valve diseases
Bicuspid aortic valve
Blood flow
Dilatation
Wall shear stress

ASJC Scopus subject areas

Medicine(all)
Biochemistry, Genetics and Molecular Biology(all)

Access to Document

10.1007/978-3-7091-4874-7_29

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Markl, M., Fedak, P. W. M., & Barker, A. (2019). Impact of aortopathy and aortic valve disease on 3d blood flow and wall shear stress in the thoracic aorta: As assessed by 4D flow MRI. In Surgical Management of Aortic Pathology: Current Fundamentals for the Clinical Management of Aortic Disease (pp. 447-464). Springer International Publishing. https://doi.org/10.1007/978-3-7091-4874-7_29

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abstract = "Recent advances in magnetic resonance imaging (MRI) allow for the comprehensive visualization and quantification of in vivo aortic 3D hemodynamics using 4D flow MRI. The technique offers the opportunity to derive advanced hemodynamic measures, such as wall shear stress, for an improved characterization of aortic disease beyond simple flow metrics known to be associated with aortopathy and aortic valve disease. This chapter will provide an introduction to 4D flow MRI as it is currently used for blood flow visualization and quantification of flow parameters and wall shear stress in the setting of aortopathy and aortic valve diseases with a focus on congenially abnormal bicuspid aortic valves and aortic stenosis.",

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Markl, M, Fedak, PWM & Barker, A 2019, Impact of aortopathy and aortic valve disease on 3d blood flow and wall shear stress in the thoracic aorta: As assessed by 4D flow MRI. in Surgical Management of Aortic Pathology: Current Fundamentals for the Clinical Management of Aortic Disease. Springer International Publishing, pp. 447-464. https://doi.org/10.1007/978-3-7091-4874-7_29

Impact of aortopathy and aortic valve disease on 3d blood flow and wall shear stress in the thoracic aorta : As assessed by 4D flow MRI. / Markl, Michael; Fedak, Paul W.M.; Barker, Alex.

Surgical Management of Aortic Pathology: Current Fundamentals for the Clinical Management of Aortic Disease. Springer International Publishing, 2019. p. 447-464.

Research output: Chapter in Book/Report/Conference proceeding › Chapter

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Markl M, Fedak PWM, Barker A. Impact of aortopathy and aortic valve disease on 3d blood flow and wall shear stress in the thoracic aorta: As assessed by 4D flow MRI. In Surgical Management of Aortic Pathology: Current Fundamentals for the Clinical Management of Aortic Disease. Springer International Publishing. 2019. p. 447-464 https://doi.org/10.1007/978-3-7091-4874-7_29