Impact of pre- and postoperative multimodality therapy on rectal cancer

Anne Marie Boller, Robert R. Cima*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

7 Scopus citations


Surgery is the primary treatment of rectal cancer. However, variability in surgical outcomes led to development of combined therapies including pelvic radiation and systemic chemotherapy. The evolution of these therapies both individually and combined, their successes and limitations is discussed in the context of an evolving understanding of rectal cancer biology. The impact of standardized optimal surgery on the need for additional therapy and trends in treating complete responders to neoadjuvant therapy is also reviewed.

Original languageEnglish (US)
Pages (from-to)665-670
Number of pages6
JournalJournal of surgical oncology
Issue number8
StatePublished - Dec 15 2007


  • Neoadjuvant therapy
  • Pelvic radiation
  • Recurrence

ASJC Scopus subject areas

  • Surgery
  • Oncology


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