Impact of pre- and postoperative multimodality therapy on rectal cancer

Anne Marie Boller; Robert R. Cima

doi:10.1002/jso.20919

Impact of pre- and postoperative multimodality therapy on rectal cancer

Anne Marie Boller, Robert R. Cima^*

^*Corresponding author for this work

Surgery, Gastrointestinal/Endocrinology Division

Research output: Contribution to journal › Review article › peer-review

7 Scopus citations

Abstract

Surgery is the primary treatment of rectal cancer. However, variability in surgical outcomes led to development of combined therapies including pelvic radiation and systemic chemotherapy. The evolution of these therapies both individually and combined, their successes and limitations is discussed in the context of an evolving understanding of rectal cancer biology. The impact of standardized optimal surgery on the need for additional therapy and trends in treating complete responders to neoadjuvant therapy is also reviewed.

Original language	English (US)
Pages (from-to)	665-670
Number of pages	6
Journal	Journal of surgical oncology
Volume	96
Issue number	8
DOIs	https://doi.org/10.1002/jso.20919
State	Published - Dec 15 2007

Keywords

Neoadjuvant therapy
Pelvic radiation
Recurrence

ASJC Scopus subject areas

Surgery
Oncology

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1002/jso.20919

Cite this

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title = "Impact of pre- and postoperative multimodality therapy on rectal cancer",

abstract = "Surgery is the primary treatment of rectal cancer. However, variability in surgical outcomes led to development of combined therapies including pelvic radiation and systemic chemotherapy. The evolution of these therapies both individually and combined, their successes and limitations is discussed in the context of an evolving understanding of rectal cancer biology. The impact of standardized optimal surgery on the need for additional therapy and trends in treating complete responders to neoadjuvant therapy is also reviewed.",

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AU - Boller, Anne Marie

AU - Cima, Robert R.

PY - 2007/12/15

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N2 - Surgery is the primary treatment of rectal cancer. However, variability in surgical outcomes led to development of combined therapies including pelvic radiation and systemic chemotherapy. The evolution of these therapies both individually and combined, their successes and limitations is discussed in the context of an evolving understanding of rectal cancer biology. The impact of standardized optimal surgery on the need for additional therapy and trends in treating complete responders to neoadjuvant therapy is also reviewed.

AB - Surgery is the primary treatment of rectal cancer. However, variability in surgical outcomes led to development of combined therapies including pelvic radiation and systemic chemotherapy. The evolution of these therapies both individually and combined, their successes and limitations is discussed in the context of an evolving understanding of rectal cancer biology. The impact of standardized optimal surgery on the need for additional therapy and trends in treating complete responders to neoadjuvant therapy is also reviewed.

KW - Neoadjuvant therapy

KW - Pelvic radiation

KW - Recurrence

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U2 - 10.1002/jso.20919

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M3 - Review article

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ER -

Impact of pre- and postoperative multimodality therapy on rectal cancer

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

Access to Document

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