Impaired continuity of flow in congenital heart disease with single ventricle physiology

Michael Markl*, Julia Geiger, Brigitte Stiller, Raoul Arnold

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

7 Scopus citations


We report the comprehensive evaluation of cardiac morphology, valve function, and three-dimensional (3D) blood flow in a pediatric patient with congenital heart disease. 3D visualization of cardiovascular flow paths and quantitative flow analysis based on flow-sensitive 4D magnetic resonance imaging (MRI) provided detailed insight into hemodynamic changes associated with valve insufficiency and the complex single ventricle physiology. Despite only moderate atrio-ventricular regurgitation (fractions28%) a marked redirection of atrial flow and pronounced vortex flow in the entire atrium was observed. Disturbed retrograde flow was even found upstream within the left pulmonary veins (regurgitant fractions27%) indicating interrupted continuity of flow directed through the single atrium and ventricle. Such findings indicate the potential of flow-sensitive 4D MRI to detect and quantify complex 3D flow alterations.

Original languageEnglish (US)
Pages (from-to)87-90
Number of pages4
JournalInteractive cardiovascular and thoracic surgery
Issue number1
StatePublished - Jan 2011


  • Blood flow
  • Cardiovascular magnetic resonance imaging
  • Congenital heart disease
  • Flow-sensitive magnetic resonance imaging

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Pulmonary and Respiratory Medicine
  • Surgery


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