Impaired varus-valgus proprioception and neuromuscular stabilization in medial knee osteoarthritis

Alison Hsin-I Chang, Song Joo Lee, Heng Zhao, Yupeng Ren, Li-Qun Zhang*

*Corresponding author for this work

Research output: Contribution to journalArticle

19 Citations (Scopus)

Abstract

Impaired proprioception and poor muscular stabilization in the frontal plane may lead to knee instability during functional activities, a common complaint in persons with knee osteoarthritis (KOA). Understanding these frontal plane neuromechanical properties in KOA will help elucidate the factors contributing to knee instability and aid in the development of targeted intervention strategies. The objectives of the study were to compare knee varus-valgus proprioception, isometric muscle strength, and active muscular contribution to stability between persons with medial KOA and healthy controls. We evaluated knee frontal plane neuromechanical parameters in 14 participants with medial KOA and 14 age- and gender-matched controls, using a joint driving device (JDD) with a customized motor and a 6-axis force sensor. Analysis of covariance with BMI as a covariate was used to test the differences in varus-valgus neuromechanical parameters between these two groups. The KOA group had impaired varus proprioception acuity (1.08±0.59° vs. 0.69±0.49°, p<0.05), decreased normalized varus muscle strength (1.31±0.75% vs. 1.79±0.84% body weight, p<0.05), a trend toward decreased valgus strength (1.29±0.67% vs. 1.88±0.99%, p=0.054), and impaired ability to actively stabilize the knee in the frontal plane during external perturbation (4.67±2.86 vs. 8.26±5.95. Nm/degree, p<0.05). The knee frontal plane sensorimotor control system is compromised in persons with medial KOA. Our findings suggest varus-valgus control deficits in both the afferent input (proprioceptive acuity) and muscular effectors (muscle strength and capacity to stabilize the joint).

Original languageEnglish (US)
Pages (from-to)360-366
Number of pages7
JournalJournal of Biomechanics
Volume47
Issue number2
DOIs
StatePublished - Jan 22 2014

Fingerprint

Proprioception
Knee Osteoarthritis
Muscle
Knee
Stabilization
Muscle Strength
Joints
Control systems
Aptitude
Sensors
Body Weight
Equipment and Supplies

Keywords

  • Instability
  • Knee osteoarthritis
  • Proprioception
  • Varus-valgus motion

ASJC Scopus subject areas

  • Biophysics
  • Orthopedics and Sports Medicine
  • Biomedical Engineering
  • Rehabilitation

Cite this

Chang, Alison Hsin-I ; Lee, Song Joo ; Zhao, Heng ; Ren, Yupeng ; Zhang, Li-Qun. / Impaired varus-valgus proprioception and neuromuscular stabilization in medial knee osteoarthritis. In: Journal of Biomechanics. 2014 ; Vol. 47, No. 2. pp. 360-366.
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abstract = "Impaired proprioception and poor muscular stabilization in the frontal plane may lead to knee instability during functional activities, a common complaint in persons with knee osteoarthritis (KOA). Understanding these frontal plane neuromechanical properties in KOA will help elucidate the factors contributing to knee instability and aid in the development of targeted intervention strategies. The objectives of the study were to compare knee varus-valgus proprioception, isometric muscle strength, and active muscular contribution to stability between persons with medial KOA and healthy controls. We evaluated knee frontal plane neuromechanical parameters in 14 participants with medial KOA and 14 age- and gender-matched controls, using a joint driving device (JDD) with a customized motor and a 6-axis force sensor. Analysis of covariance with BMI as a covariate was used to test the differences in varus-valgus neuromechanical parameters between these two groups. The KOA group had impaired varus proprioception acuity (1.08±0.59° vs. 0.69±0.49°, p<0.05), decreased normalized varus muscle strength (1.31±0.75{\%} vs. 1.79±0.84{\%} body weight, p<0.05), a trend toward decreased valgus strength (1.29±0.67{\%} vs. 1.88±0.99{\%}, p=0.054), and impaired ability to actively stabilize the knee in the frontal plane during external perturbation (4.67±2.86 vs. 8.26±5.95. Nm/degree, p<0.05). The knee frontal plane sensorimotor control system is compromised in persons with medial KOA. Our findings suggest varus-valgus control deficits in both the afferent input (proprioceptive acuity) and muscular effectors (muscle strength and capacity to stabilize the joint).",
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Impaired varus-valgus proprioception and neuromuscular stabilization in medial knee osteoarthritis. / Chang, Alison Hsin-I; Lee, Song Joo; Zhao, Heng; Ren, Yupeng; Zhang, Li-Qun.

In: Journal of Biomechanics, Vol. 47, No. 2, 22.01.2014, p. 360-366.

Research output: Contribution to journalArticle

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AU - Lee, Song Joo

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