Implantable, Bioresorbable Radio Frequency Resonant Circuits for Magnetic Resonance Imaging

Geumbee Lee, Mark D. Does*, Raudel Avila, Juyeon Kang, Kevin D. Harkins, Yunyun Wu, William E. Banks, Minsu Park, Di Lu, Xinqiang Yan, Jong Uk Kim, Sang Min Won, Adam G. Evans, Jeremy T. Joseph, Christopher L. Kalmar, Alonda C. Pollins, Huseyin Karagoz, Wesley P. Thayer, Yonggang Huang, John A. Rogers*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

4 Scopus citations


Magnetic resonance imaging (MRI) is widely used in clinical care and medical research. The signal-to-noise ratio (SNR) in the measurement affects parameters that determine the diagnostic value of the image, such as the spatial resolution, contrast, and scan time. Surgically implanted radiofrequency coils can increase SNR of subsequent MRI studies of adjacent tissues. The resulting benefits in SNR are, however, balanced by significant risks associated with surgically removing these coils or with leaving them in place permanently. As an alternative, here the authors report classes of implantable inductor–capacitor circuits made entirely of bioresorbable organic and inorganic materials. Engineering choices for the designs of an inductor and a capacitor provide the ability to select the resonant frequency of the devices to meet MRI specifications (e.g., 200 MHz at 4.7 T MRI). Such devices enhance the SNR and improve the associated imaging capabilities. These simple, small bioelectronic systems function over clinically relevant time frames (up to 1 month) at physiological conditions and then disappear completely by natural mechanisms of bioresorption, thereby eliminating the need for surgical extraction. Imaging demonstrations in a nerve phantom and a human cadaver suggest that this technology has broad potential for post-surgical monitoring/evaluation of recovery processes.

Original languageEnglish (US)
JournalAdvanced Science
StateAccepted/In press - 2023


  • LC-resonant circuits
  • biomedical implants
  • bioresorbable devices
  • magnetic resonance imaging
  • radiofrequency coils

ASJC Scopus subject areas

  • General Engineering
  • General Physics and Astronomy
  • General Chemical Engineering
  • General Materials Science
  • Biochemistry, Genetics and Molecular Biology (miscellaneous)
  • Medicine (miscellaneous)


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